LEF1/beta-catenin complex regulates transcription of the Cav3.1 calcium channel gene (Cacna1g) in thalamic neurons of the adult brain

beta-Catenin, together with LEF1/TCF transcription factors, activates genes involved in the proliferation and differentiation of neuronal precursor cells. In mature neurons, beta-catenin participates in dendritogenesis and synaptic function as a component of the cadherin cell adhesion complex. Howev...

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Veröffentlicht in:	The Journal of neuroscience 2010-04, Vol.30 (14), p.4957-4969
Hauptverfasser:	Wisniewska, Marta B, Misztal, Katarzyna, Michowski, Wojciech, Szczot, Marcin, Purta, Elzbieta, Lesniak, Wieslawa, Klejman, Monika E, Dabrowski, Michal, Filipkowski, Robert K, Nagalski, Andrzej, Mozrzymas, Jerzy W, Kuznicki, Jacek
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Factors Animals beta Catenin - chemistry beta Catenin - physiology Calcium Channels, T-Type - biosynthesis Calcium Channels, T-Type - chemistry Calcium Channels, T-Type - genetics Cells, Cultured Female HeLa Cells Humans Lymphoid Enhancer-Binding Factor 1 - chemistry Lymphoid Enhancer-Binding Factor 1 - physiology Male Mice Neurons - physiology Rats Synapses - chemistry Synapses - genetics Synapses - metabolism Thalamus - physiology Transcriptional Activation - physiology
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