Natural Antioxidant Anthocyanins-A Hidden Therapeutic Candidate in Metabolic Disorders with Major Focus in Neurodegeneration

All over the world, metabolic syndrome constitutes severe health problems. Multiple factors have been reported in the pathogenesis of metabolic syndrome. Metabolic disorders result in reactive oxygen species (ROS) induced oxidative stress, playing a vital role in the development and pathogenesis of...

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Veröffentlicht in:	Nutrients 2019-05, Vol.11 (6), p.1195
Hauptverfasser:	Ullah, Rahat, Khan, Mehtab, Shah, Shahid Ali, Saeed, Kamran, Kim, Myeong Ok
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Phosphatidylinositol 3-kinase Activation adverse effects AKT protein Alzheimer's disease Animals Anthocyanins Anthocyanins - adverse effects Anthocyanins - therapeutic use antioxidant activity Antioxidants Antioxidants - adverse effects Antioxidants - therapeutic use Apoptosis Brain Brain - drug effects Brain - metabolism Brain - pathology Cholesterol Cyclooxygenase-2 D-Galactose Deoxyribonucleic acid Detoxification Diabetes DNA DNA adducts Enzymatic activity Ethanol Flavonoids Free radicals fruits Galactose Glutamatergic transmission Hippocampus Humans Hydrogen peroxide Hyperglycemia Hypertension inflammation Inflammation Mediators - metabolism Low level medicinal plants metabolic diseases Metabolic disorders Metabolic syndrome Metabolic Syndrome - drug therapy Metabolic Syndrome - metabolism metabolism mitochondria NAD(P)H oxidase nanoparticles Nerve Degeneration Neurodegeneration neurodegenerative diseases Neurodegenerative Diseases - drug therapy Neurodegenerative Diseases - metabolism Neurodegenerative Diseases - pathology Neuroprotective Agents - adverse effects Neuroprotective Agents - therapeutic use Nitrogen Nonsteroidal anti-inflammatory drugs Oxidation Oxidative stress Oxidative Stress - drug effects Parkinson's disease Pathogenesis peripheral nervous system diseases polyphenols reactive oxygen species Reactive Oxygen Species - metabolism Review Signal Transduction therapeutics Toxicity Xanthine oxidase
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