Single-cell RNA-Seq analysis identifies a putative epithelial stem cell population in human primary prostate cells in monolayer and organoid culture conditions

Human primary prostate epithelial (PrE) cells represent patient-derived models and are traditionally grown as a monolayer in two-dimensional culture. It has been recently demonstrated that expansion of primary cells into three-dimensional prostatic organoids better mimics prostate epithelial glands...

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Veröffentlicht in:	American journal of clinical and experimental urology 2019-01, Vol.7 (3), p.123-138
Hauptverfasser:	McCray, Tara, Moline, Daniel, Baumann, Bethany, Vander Griend, Donald J, Nonn, Larisa
Format:	Artikel
Sprache:	eng
Schlagworte:	Original
Online-Zugang:	Volltext
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