The re-emerging association between tuberculosis and diabetes: Lessons from past centuries
The association between tuberculosis (TB) and diabetes mellitus (DM) had a common place in the literature up to the first half of the 20th century, but virtually disappeared with the discovery of insulin to treat DM and antibiotics to cure TB. In the late 1990s the literature began to re-emerge with...
Gespeichert in:
Veröffentlicht in: | Tuberculosis (Edinburgh, Scotland) Scotland), 2019-05, Vol.116, p.S89-S97 |
---|---|
Hauptverfasser: | , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | S97 |
---|---|
container_issue | |
container_start_page | S89 |
container_title | Tuberculosis (Edinburgh, Scotland) |
container_volume | 116 |
creator | Cadena, Jose Rathinavelu, Selvalakshmi Lopez-Alvarenga, Juan C. Restrepo, Blanca I. |
description | The association between tuberculosis (TB) and diabetes mellitus (DM) had a common place in the literature up to the first half of the 20th century, but virtually disappeared with the discovery of insulin to treat DM and antibiotics to cure TB. In the late 1990s the literature began to re-emerge with the worldwide increase in type 2 DM, particularly in TB-endemic countries. Today, type 2 DM is the most prevalent comorbidity among TB patients and the World Health Organization considers it a threat to TB control. We summarize the literature on TB and DM up to the 1960s. Then we evaluate unique aspects of this comorbidity in older times, such as the frequent diabetic comas that suggest challenges for proper DM management as insulin was being implemented, or the absence of antibiotics to cure TB. Despite the unique aspects of each study period, the literature across times is consistent in key aspects of the association. Namely, a higher TB prevalence among DM (versus non-DM patients), the importance of glucose control and chronic DM on TB susceptibility and the higher risk of death among patients with the co-morbidity. From the older literature, we can infer the likely contribution of type 1 DM to TB (in addition to type 2), regardless of their differing autoimmune or metabolic pathophysiology, respectively. Furthermore, in the older literature there was a notable reporting of DM development among TB patients, even though DM usually preceded TB. This observation deserves further epidemiological and basic studies to elucidate this intriguing aspect of the relationship between TB and DM. |
doi_str_mv | 10.1016/j.tube.2019.04.015 |
format | Article |
fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6626679</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S1472979219301544</els_id><sourcerecordid>2232023245</sourcerecordid><originalsourceid>FETCH-LOGICAL-c455t-ec5aa11ff8ee062ecc4bb2e74174b6829ab1bd3e0a516831db69268ee7f5ee433</originalsourceid><addsrcrecordid>eNp9kUtr3DAUhUVpaV79A1kULbuxI8mybJdSKCGPwkA3KYRuhCRfTzTY0lTXTum_r8wkod10ISS43zlH3EPIOWclZ1xd7Mp5sVAKxruSyZLx-hU55m1TFaLl96_zWzai6JpOHJETxB3LItayt-So4qytueiOyY-7B6AJCpggbX3YUoMYnTezj4FamH8BBLrGJLeMET1SE3rae5NngB_pBjIfkA4pTnRvcKYOwrwkD3hG3gxmRHj3dJ-S79dXd5e3xebbzdfLL5vCybqeC3C1MZwPQwvAlADnpLUCGskbaVUrOmO57StgpuaqrXhvVSdUhpuhBpBVdUo-H3z3i52gX_OTGfU--cmk3zoar_-dBP-gt_FRKyWUarps8OHJIMWfC-CsJ48OxtEEiAtqISrB8pF1RsUBdSkiJhheYjjTayl6p9dt6bUUzaTOpWTR-78_-CJ5biEDnw4A5DU9ekganYfgoPcJ3Kz76P_n_weJgqEx</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2232023245</pqid></control><display><type>article</type><title>The re-emerging association between tuberculosis and diabetes: Lessons from past centuries</title><source>MEDLINE</source><source>Access via ScienceDirect (Elsevier)</source><creator>Cadena, Jose ; Rathinavelu, Selvalakshmi ; Lopez-Alvarenga, Juan C. ; Restrepo, Blanca I.</creator><creatorcontrib>Cadena, Jose ; Rathinavelu, Selvalakshmi ; Lopez-Alvarenga, Juan C. ; Restrepo, Blanca I.</creatorcontrib><description>The association between tuberculosis (TB) and diabetes mellitus (DM) had a common place in the literature up to the first half of the 20th century, but virtually disappeared with the discovery of insulin to treat DM and antibiotics to cure TB. In the late 1990s the literature began to re-emerge with the worldwide increase in type 2 DM, particularly in TB-endemic countries. Today, type 2 DM is the most prevalent comorbidity among TB patients and the World Health Organization considers it a threat to TB control. We summarize the literature on TB and DM up to the 1960s. Then we evaluate unique aspects of this comorbidity in older times, such as the frequent diabetic comas that suggest challenges for proper DM management as insulin was being implemented, or the absence of antibiotics to cure TB. Despite the unique aspects of each study period, the literature across times is consistent in key aspects of the association. Namely, a higher TB prevalence among DM (versus non-DM patients), the importance of glucose control and chronic DM on TB susceptibility and the higher risk of death among patients with the co-morbidity. From the older literature, we can infer the likely contribution of type 1 DM to TB (in addition to type 2), regardless of their differing autoimmune or metabolic pathophysiology, respectively. Furthermore, in the older literature there was a notable reporting of DM development among TB patients, even though DM usually preceded TB. This observation deserves further epidemiological and basic studies to elucidate this intriguing aspect of the relationship between TB and DM.</description><identifier>ISSN: 1472-9792</identifier><identifier>EISSN: 1873-281X</identifier><identifier>DOI: 10.1016/j.tube.2019.04.015</identifier><identifier>PMID: 31085129</identifier><language>eng</language><publisher>Scotland: Elsevier Ltd</publisher><subject>Animals ; Comorbidity ; Death ; Diabetes Mellitus, Type 1 - diagnosis ; Diabetes Mellitus, Type 1 - epidemiology ; Diabetes Mellitus, Type 1 - history ; Diabetes Mellitus, Type 1 - mortality ; Diabetes Mellitus, Type 2 - diagnosis ; Diabetes Mellitus, Type 2 - epidemiology ; Diabetes Mellitus, Type 2 - history ; Diabetes Mellitus, Type 2 - mortality ; History ; History, 19th Century ; History, 20th Century ; History, 21st Century ; Humans ; Incidence ; Prevalence ; Prognosis ; Risk Assessment ; Risk Factors ; Time Factors ; Treatment outcomes ; Tuberculosis ; Tuberculosis - diagnosis ; Tuberculosis - epidemiology ; Tuberculosis - history ; Tuberculosis - mortality ; Type 1 diabetes ; Type 2 diabetes</subject><ispartof>Tuberculosis (Edinburgh, Scotland), 2019-05, Vol.116, p.S89-S97</ispartof><rights>2019 Elsevier Ltd</rights><rights>Copyright © 2019 Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c455t-ec5aa11ff8ee062ecc4bb2e74174b6829ab1bd3e0a516831db69268ee7f5ee433</citedby><cites>FETCH-LOGICAL-c455t-ec5aa11ff8ee062ecc4bb2e74174b6829ab1bd3e0a516831db69268ee7f5ee433</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.tube.2019.04.015$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>230,315,781,785,886,3551,27928,27929,45999</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31085129$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Cadena, Jose</creatorcontrib><creatorcontrib>Rathinavelu, Selvalakshmi</creatorcontrib><creatorcontrib>Lopez-Alvarenga, Juan C.</creatorcontrib><creatorcontrib>Restrepo, Blanca I.</creatorcontrib><title>The re-emerging association between tuberculosis and diabetes: Lessons from past centuries</title><title>Tuberculosis (Edinburgh, Scotland)</title><addtitle>Tuberculosis (Edinb)</addtitle><description>The association between tuberculosis (TB) and diabetes mellitus (DM) had a common place in the literature up to the first half of the 20th century, but virtually disappeared with the discovery of insulin to treat DM and antibiotics to cure TB. In the late 1990s the literature began to re-emerge with the worldwide increase in type 2 DM, particularly in TB-endemic countries. Today, type 2 DM is the most prevalent comorbidity among TB patients and the World Health Organization considers it a threat to TB control. We summarize the literature on TB and DM up to the 1960s. Then we evaluate unique aspects of this comorbidity in older times, such as the frequent diabetic comas that suggest challenges for proper DM management as insulin was being implemented, or the absence of antibiotics to cure TB. Despite the unique aspects of each study period, the literature across times is consistent in key aspects of the association. Namely, a higher TB prevalence among DM (versus non-DM patients), the importance of glucose control and chronic DM on TB susceptibility and the higher risk of death among patients with the co-morbidity. From the older literature, we can infer the likely contribution of type 1 DM to TB (in addition to type 2), regardless of their differing autoimmune or metabolic pathophysiology, respectively. Furthermore, in the older literature there was a notable reporting of DM development among TB patients, even though DM usually preceded TB. This observation deserves further epidemiological and basic studies to elucidate this intriguing aspect of the relationship between TB and DM.</description><subject>Animals</subject><subject>Comorbidity</subject><subject>Death</subject><subject>Diabetes Mellitus, Type 1 - diagnosis</subject><subject>Diabetes Mellitus, Type 1 - epidemiology</subject><subject>Diabetes Mellitus, Type 1 - history</subject><subject>Diabetes Mellitus, Type 1 - mortality</subject><subject>Diabetes Mellitus, Type 2 - diagnosis</subject><subject>Diabetes Mellitus, Type 2 - epidemiology</subject><subject>Diabetes Mellitus, Type 2 - history</subject><subject>Diabetes Mellitus, Type 2 - mortality</subject><subject>History</subject><subject>History, 19th Century</subject><subject>History, 20th Century</subject><subject>History, 21st Century</subject><subject>Humans</subject><subject>Incidence</subject><subject>Prevalence</subject><subject>Prognosis</subject><subject>Risk Assessment</subject><subject>Risk Factors</subject><subject>Time Factors</subject><subject>Treatment outcomes</subject><subject>Tuberculosis</subject><subject>Tuberculosis - diagnosis</subject><subject>Tuberculosis - epidemiology</subject><subject>Tuberculosis - history</subject><subject>Tuberculosis - mortality</subject><subject>Type 1 diabetes</subject><subject>Type 2 diabetes</subject><issn>1472-9792</issn><issn>1873-281X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kUtr3DAUhUVpaV79A1kULbuxI8mybJdSKCGPwkA3KYRuhCRfTzTY0lTXTum_r8wkod10ISS43zlH3EPIOWclZ1xd7Mp5sVAKxruSyZLx-hU55m1TFaLl96_zWzai6JpOHJETxB3LItayt-So4qytueiOyY-7B6AJCpggbX3YUoMYnTezj4FamH8BBLrGJLeMET1SE3rae5NngB_pBjIfkA4pTnRvcKYOwrwkD3hG3gxmRHj3dJ-S79dXd5e3xebbzdfLL5vCybqeC3C1MZwPQwvAlADnpLUCGskbaVUrOmO57StgpuaqrXhvVSdUhpuhBpBVdUo-H3z3i52gX_OTGfU--cmk3zoar_-dBP-gt_FRKyWUarps8OHJIMWfC-CsJ48OxtEEiAtqISrB8pF1RsUBdSkiJhheYjjTayl6p9dt6bUUzaTOpWTR-78_-CJ5biEDnw4A5DU9ekganYfgoPcJ3Kz76P_n_weJgqEx</recordid><startdate>201905</startdate><enddate>201905</enddate><creator>Cadena, Jose</creator><creator>Rathinavelu, Selvalakshmi</creator><creator>Lopez-Alvarenga, Juan C.</creator><creator>Restrepo, Blanca I.</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>201905</creationdate><title>The re-emerging association between tuberculosis and diabetes: Lessons from past centuries</title><author>Cadena, Jose ; Rathinavelu, Selvalakshmi ; Lopez-Alvarenga, Juan C. ; Restrepo, Blanca I.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c455t-ec5aa11ff8ee062ecc4bb2e74174b6829ab1bd3e0a516831db69268ee7f5ee433</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Animals</topic><topic>Comorbidity</topic><topic>Death</topic><topic>Diabetes Mellitus, Type 1 - diagnosis</topic><topic>Diabetes Mellitus, Type 1 - epidemiology</topic><topic>Diabetes Mellitus, Type 1 - history</topic><topic>Diabetes Mellitus, Type 1 - mortality</topic><topic>Diabetes Mellitus, Type 2 - diagnosis</topic><topic>Diabetes Mellitus, Type 2 - epidemiology</topic><topic>Diabetes Mellitus, Type 2 - history</topic><topic>Diabetes Mellitus, Type 2 - mortality</topic><topic>History</topic><topic>History, 19th Century</topic><topic>History, 20th Century</topic><topic>History, 21st Century</topic><topic>Humans</topic><topic>Incidence</topic><topic>Prevalence</topic><topic>Prognosis</topic><topic>Risk Assessment</topic><topic>Risk Factors</topic><topic>Time Factors</topic><topic>Treatment outcomes</topic><topic>Tuberculosis</topic><topic>Tuberculosis - diagnosis</topic><topic>Tuberculosis - epidemiology</topic><topic>Tuberculosis - history</topic><topic>Tuberculosis - mortality</topic><topic>Type 1 diabetes</topic><topic>Type 2 diabetes</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cadena, Jose</creatorcontrib><creatorcontrib>Rathinavelu, Selvalakshmi</creatorcontrib><creatorcontrib>Lopez-Alvarenga, Juan C.</creatorcontrib><creatorcontrib>Restrepo, Blanca I.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Tuberculosis (Edinburgh, Scotland)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cadena, Jose</au><au>Rathinavelu, Selvalakshmi</au><au>Lopez-Alvarenga, Juan C.</au><au>Restrepo, Blanca I.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The re-emerging association between tuberculosis and diabetes: Lessons from past centuries</atitle><jtitle>Tuberculosis (Edinburgh, Scotland)</jtitle><addtitle>Tuberculosis (Edinb)</addtitle><date>2019-05</date><risdate>2019</risdate><volume>116</volume><spage>S89</spage><epage>S97</epage><pages>S89-S97</pages><issn>1472-9792</issn><eissn>1873-281X</eissn><abstract>The association between tuberculosis (TB) and diabetes mellitus (DM) had a common place in the literature up to the first half of the 20th century, but virtually disappeared with the discovery of insulin to treat DM and antibiotics to cure TB. In the late 1990s the literature began to re-emerge with the worldwide increase in type 2 DM, particularly in TB-endemic countries. Today, type 2 DM is the most prevalent comorbidity among TB patients and the World Health Organization considers it a threat to TB control. We summarize the literature on TB and DM up to the 1960s. Then we evaluate unique aspects of this comorbidity in older times, such as the frequent diabetic comas that suggest challenges for proper DM management as insulin was being implemented, or the absence of antibiotics to cure TB. Despite the unique aspects of each study period, the literature across times is consistent in key aspects of the association. Namely, a higher TB prevalence among DM (versus non-DM patients), the importance of glucose control and chronic DM on TB susceptibility and the higher risk of death among patients with the co-morbidity. From the older literature, we can infer the likely contribution of type 1 DM to TB (in addition to type 2), regardless of their differing autoimmune or metabolic pathophysiology, respectively. Furthermore, in the older literature there was a notable reporting of DM development among TB patients, even though DM usually preceded TB. This observation deserves further epidemiological and basic studies to elucidate this intriguing aspect of the relationship between TB and DM.</abstract><cop>Scotland</cop><pub>Elsevier Ltd</pub><pmid>31085129</pmid><doi>10.1016/j.tube.2019.04.015</doi><oa>free_for_read</oa></addata></record> |
fulltext | fulltext |
identifier | ISSN: 1472-9792 |
ispartof | Tuberculosis (Edinburgh, Scotland), 2019-05, Vol.116, p.S89-S97 |
issn | 1472-9792 1873-281X |
language | eng |
recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6626679 |
source | MEDLINE; Access via ScienceDirect (Elsevier) |
subjects | Animals Comorbidity Death Diabetes Mellitus, Type 1 - diagnosis Diabetes Mellitus, Type 1 - epidemiology Diabetes Mellitus, Type 1 - history Diabetes Mellitus, Type 1 - mortality Diabetes Mellitus, Type 2 - diagnosis Diabetes Mellitus, Type 2 - epidemiology Diabetes Mellitus, Type 2 - history Diabetes Mellitus, Type 2 - mortality History History, 19th Century History, 20th Century History, 21st Century Humans Incidence Prevalence Prognosis Risk Assessment Risk Factors Time Factors Treatment outcomes Tuberculosis Tuberculosis - diagnosis Tuberculosis - epidemiology Tuberculosis - history Tuberculosis - mortality Type 1 diabetes Type 2 diabetes |
title | The re-emerging association between tuberculosis and diabetes: Lessons from past centuries |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-17T02%3A15%3A37IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20re-emerging%20association%20between%20tuberculosis%20and%20diabetes:%20Lessons%20from%20past%20centuries&rft.jtitle=Tuberculosis%20(Edinburgh,%20Scotland)&rft.au=Cadena,%20Jose&rft.date=2019-05&rft.volume=116&rft.spage=S89&rft.epage=S97&rft.pages=S89-S97&rft.issn=1472-9792&rft.eissn=1873-281X&rft_id=info:doi/10.1016/j.tube.2019.04.015&rft_dat=%3Cproquest_pubme%3E2232023245%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2232023245&rft_id=info:pmid/31085129&rft_els_id=S1472979219301544&rfr_iscdi=true |