Molecular and functional imaging insights into the role of hypoxia in cancer aggression

Hypoxia in cancers has evoked significant interest since 1955 when Thomlinson and Gray postulated the presence of hypoxia in human lung cancers, based on the observation of necrosis occurring at the diffusion limit of oxygen from the nearest blood vessel, and identified the implication of these obse...

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Veröffentlicht in:	Cancer and metastasis reviews 2019-06, Vol.38 (1-2), p.51-64
Hauptverfasser:	Kakkad, Samata, Krishnamachary, Balaji, Jacob, Desmond, Pacheco-Torres, Jesus, Goggins, Eibhlin, Bharti, Santosh Kumar, Penet, Marie-France, Bhujwalla, Zaver M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acidosis Animals Biomedical and Life Sciences Biomedicine Cancer Cancer Research Cancer therapies Gene regulation Heterogeneity Humans Hypoxia Hypoxia-inducible factors Lung cancer Lungs Magnetic Resonance Imaging Microenvironments Neoplasm Metastasis Neoplasms - blood supply Neoplasms - diagnostic imaging Neoplasms - metabolism Oncology Oxygenation Positron-Emission Tomography Precision medicine Radiation Radiation therapy Radiotherapy Transcription Tumor Hypoxia - physiology Tumors
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