Interaction of BDNF and COMT polymorphisms on paired-associative stimulation-induced cortical plasticity

The common single-nucleotide polymorphism (SNP) brain-derived neurotrophic factor (BDNF) valine-to-methionine substitution at codon 66 (Val66Met) has been associated with differences in memory functions and cortical plasticity following brain stimulation. Other studies could not confirm these result...

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Veröffentlicht in:	The Journal of neuroscience 2012-03, Vol.32 (13), p.4553-4561
Hauptverfasser:	Witte, A Veronica, Kürten, Julia, Jansen, Stefanie, Schirmacher, Anja, Brand, Eva, Sommer, Jens, Flöel, Agnes
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Brain-Derived Neurotrophic Factor - genetics Brain-Derived Neurotrophic Factor - physiology Catechol O-Methyltransferase - genetics Catechol O-Methyltransferase - physiology Cerebral Cortex - physiology Cognition - physiology Female Genotype Heterozygote Humans Intracellular Signaling Peptides and Proteins - genetics Intracellular Signaling Peptides and Proteins - physiology Learning - physiology Neuronal Plasticity - genetics Neuronal Plasticity - physiology Neuropsychological Tests - statistics & numerical data Phosphoproteins - genetics Phosphoproteins - physiology Polymorphism, Single Nucleotide - physiology Psychomotor Performance - physiology Transcranial Magnetic Stimulation - methods Transcranial Magnetic Stimulation - psychology
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