Purinergic modulation of neuronal activity in developing auditory brainstem

In the developing nervous system, spontaneous neuronal activity arises independently of experience or any environmental input. This activity may play a major role in axonal pathfinding, refinement of topographic maps, dendritic morphogenesis, and the segregation of axonal terminal arbors. In the aud...

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Veröffentlicht in:	The Journal of neuroscience 2012-08, Vol.32 (31), p.10699-10712
Hauptverfasser:	Dietz, Beatrice, Jovanovic, Saša, Wielsch, Betty, Nerlich, Jana, Rübsamen, Rudolf, Milenkovic, Ivan
Format:	Artikel
Sprache:	eng
Schlagworte:	Acoustic Stimulation Action Potentials - drug effects Action Potentials - physiology Adenosine Triphosphate - analogs & derivatives Adenosine Triphosphate - metabolism Adenosine Triphosphate - pharmacology Age Factors Analysis of Variance Animals Animals, Newborn Brain Stem - cytology Brain Stem - growth & development Calcium - metabolism Dose-Response Relationship, Drug Drug Interactions Electric Stimulation Excitatory Amino Acid Antagonists - pharmacology Female Gerbillinae Glycine - pharmacology In Vitro Techniques Kynurenic Acid - pharmacology Male Meriones unguiculatus Patch-Clamp Techniques Psychoacoustics Receptors, Purinergic P2X - metabolism Sensory Receptor Cells - drug effects Sensory Receptor Cells - physiology Signal Transduction - drug effects Stilbamidines - metabolism Synaptic Potentials - drug effects
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