Striatal indirect pathway contributes to selection accuracy of learned motor actions

The dorsal striatum, which contains the dorsolateral striatum (DLS) and dorsomedial striatum (DMS), integrates the acquisition and implementation of instrumental learning in cooperation with the nucleus accumbens (NAc). The dorsal striatum regulates the basal ganglia circuitry through direct and ind...

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Veröffentlicht in:	The Journal of neuroscience 2012-09, Vol.32 (39), p.13421-13432
Hauptverfasser:	Nishizawa, Kayo, Fukabori, Ryoji, Okada, Kana, Kai, Nobuyuki, Uchigashima, Motokazu, Watanabe, Masahiko, Shiota, Akira, Ueda, Masatsugu, Tsutsui, Yuji, Kobayashi, Kazuto
Format:	Artikel
Sprache:	eng
Schlagworte:	Acoustic Stimulation Analysis of Variance Animals Animals, Genetically Modified Biotin - analogs & derivatives Calbindin 2 Choice Behavior - drug effects Choice Behavior - physiology Choline O-Acetyltransferase - metabolism Conditioning, Operant - drug effects Conditioning, Operant - physiology Corpus Striatum - cytology Corpus Striatum - injuries Corpus Striatum - physiology Dextrans Discrimination, Psychological - physiology Dopaminergic Neurons - drug effects Enkephalins - genetics Enkephalins - metabolism Female Gene Expression Regulation - drug effects Gene Expression Regulation - genetics Ibotenic Acid - toxicity Immunotoxins - toxicity Interneurons - metabolism Male Motivation - drug effects Motivation - genetics Motor Activity - physiology Parvalbumins - metabolism Phosphopyruvate Hydratase - metabolism Protein Precursors - genetics Protein Precursors - metabolism Rats Rats, Long-Evans Reaction Time - drug effects Reaction Time - genetics Receptors, Dopamine D2 - deficiency Receptors, Dopamine D2 - metabolism Receptors, Interleukin-2 - genetics Reinforcement Schedule S100 Calcium Binding Protein G - metabolism Substantia Nigra - metabolism Tachykinins - genetics Tachykinins - metabolism Tyrosine 3-Monooxygenase - metabolism Ventral Tegmental Area - metabolism
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