Multimodal porogen platforms for calcium phosphate cement degradation

Calcium phosphate cements (CPCs) represent excellent bone substitute materials due to their biocompatibility and injectability. However, their poor degradability and lack of macroporosity limits bone regeneration. The addition of poly(d,l‐lactic‐co‐glycolic acid) (PLGA) particles improves macroporos...

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Veröffentlicht in:	Journal of biomedical materials research. Part A 2019-08, Vol.107 (8), p.1713-1722
Hauptverfasser:	Lodoso‐Torrecilla, Irene, Grosfeld, Eline‐Claire, Marra, Abe, Smith, Brandon T, Mikos, Antonios G, Ulrich, Dietmar JO, Jansen, John A, van den Beucken, Jeroen JJP
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biocompatibility Biomedical materials Bone Cements - chemistry Bone growth Calcium calcium phosphate cement Calcium phosphates Calcium Phosphates - chemistry Cements Compressive strength Degradability Degradation Femur Formulations Glycolic acid Implantation Incubation Injectability Macroporosity Male Mechanical properties Original Osteogenesis Phase transitions Platforms PLGA Polylactide-co-glycolide Pore formation Porosity Prosthesis Implantation Rats, Wistar Regeneration Regeneration (physiology) Substitute bone Sucrose Sugar Surgical implants
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