Slc20a2, Encoding the Phosphate Transporter PiT2, Is an Important Genetic Determinant of Bone Quality and Strength

ABSTRACT Osteoporosis is characterized by low bone mineral density (BMD) and fragility fracture and affects over 200 million people worldwide. Bone quality describes the material properties that contribute to strength independently of BMD, and its quantitative analysis is a major priority in osteopo...

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Veröffentlicht in:	Journal of bone and mineral research 2019-06, Vol.34 (6), p.1101-1114
Hauptverfasser:	Beck‐Cormier, Sarah, Lelliott, Christopher J, Logan, John G, Lafont, David T, Merametdjian, Laure, Leitch, Victoria D, Butterfield, Natalie C, Protheroe, Hayley J, Croucher, Peter I, Baldock, Paul A, Gaultier‐Lintia, Alina, Maugars, Yves, Nicolas, Gael, Banse, Christopher, Normant, Sébastien, Magne, Nicolas, Gérardin, Emmanuel, Bon, Nina, Sourice, Sophie, Guicheux, Jérôme, Beck, Laurent, Williams, Graham R, Bassett, J H Duncan
Format:	Artikel
Sprache:	eng
Schlagworte:	ANIMAL MODELS (GENETIC ANIMAL MODELS) Bone mass BONE MATRIX (MATRIX MINERALIZATION) Bone mineral content Bone mineral density Bone strength Calcium phosphates DISORDERS OF CALCIUM/PHOSPHATE METABOLISM (OTHER) GENETIC RESEARCH (HUMAN ASSOCIATION STUDIES) Genetics Life Sciences Mineralization Original ORTHOPAEDICS (BIOMECHANICS) Ossification Osteoporosis Phosphate transporter Quality
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