Development of orthotopic tumour models using ultrasound-guided intrahepatic injection

Mouse models of human diseases are an essential part of the translational pipeline. Orthotopic tumour mouse models are increasingly being used in cancer research due to their increased clinical relevance over subcutaneous xenograft models, particularly in relation to metastatic disease. In this stud...

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Veröffentlicht in:	Scientific reports 2019-07, Vol.9 (1), p.9904-9, Article 9904
Hauptverfasser:	McVeigh, L. E., Wijetunga, I., Ingram, N., Marston, G., Prasad, R., Markham, A. F., Coletta, P. L.
Format:	Artikel
Sprache:	eng
Schlagworte:	13 13/106 13/51 59 59/5 64 64/60 692/308/1426 692/4020/1503/1504/1885 692/4020/4021/1328/1325/1326 692/4028/67/2321 Animal models Animals Bioluminescence Cancer Cholangiocarcinoma Colorectal cancer Colorectal carcinoma Colorectal Neoplasms - diagnostic imaging Colorectal Neoplasms - pathology Disease Models, Animal Female Histology Humanities and Social Sciences Humans Injection Liver cancer Liver Neoplasms - diagnostic imaging Liver Neoplasms - pathology Male Metastases Mice Mice, Inbred BALB C Mice, Nude multidisciplinary Science Science (multidisciplinary) Tumor Burden Tumor Cells, Cultured Tumors Ultrasonic imaging Ultrasonography - methods Ultrasound Xenograft Model Antitumor Assays Xenografts
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