Responsive self-assembly of tectoRNAs with loop–receptor interactions from the tetrahydrofolate (THF) riboswitch

Abstract Naturally occurring RNAs are known to exhibit a high degree of modularity, whereby specific structural modules (or motifs) can be mixed and matched to create new molecular architectures. The modular nature of RNA also affords researchers the ability to characterize individual structural ele...

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Veröffentlicht in:	Nucleic acids research 2019-07, Vol.47 (12), p.6439-6451
Hauptverfasser:	Mitchell, Charles, Polanco, Julio A, DeWald, Laura, Kress, Dustin, Jaeger, Luc, Grabow, Wade W
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding Sites Crystallography, X-Ray Leucovorin - metabolism Riboswitch RNA - chemistry RNA and RNA-protein complexes Tetrahydrofolates - metabolism Thermodynamics
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