Anti-atherosclerotic effects of LXRα agonist through induced conversion of M1 macrophage to M2

Liver X receptor alpha (LXRα) plays important roles in lipid metabolism and inflammation. Therefore, it is essential for protection against atherosclerosis (AS). In AS plaques, the key cells involved in lipid metabolism and inflammation are macrophages. However, the mechanism by which LXRα regulates...

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Veröffentlicht in:	American journal of translational research 2019-01, Vol.11 (6), p.3825-3840
Hauptverfasser:	Dou, Fangfang, Chen, Jiulin, Cao, Hui, Jia, Qingling, Shen, Dingzhu, Liu, Te, Chen, Chuan
Format:	Artikel
Sprache:	eng
Schlagworte:	Original
Online-Zugang:	Volltext
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