Iron toxicity, lipid peroxidation and ferroptosis after intracerebral haemorrhage

Intracerebral haemorrhage (ICH) is a devastating type of stroke with high mortality and morbidity. However, we have few options for ICH therapy and limited knowledge about post-ICH neuronal death and related mechanisms. In the aftermath of ICH, iron overload within the perihaematomal region can indu...

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Veröffentlicht in:	Stroke and vascular neurology 2019-06, Vol.4 (2), p.93-95
Hauptverfasser:	Wan, Jieru, Ren, Honglei, Wang, Jian
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer's disease Animals Apoptosis Autophagy Brain - drug effects Brain - metabolism Brain - pathology Brain cancer Brain damage Brain research Cerebral Hemorrhage - drug therapy Cerebral Hemorrhage - metabolism Cerebral Hemorrhage - pathology Ferroptosis Ferroptosis - drug effects Hemorrhage Humans Inflammation Iron Iron - blood Iron - metabolism Iron Chelating Agents - therapeutic use Lipid peroxidation Lipid Peroxidation - drug effects Lipids Mitochondria Oxidative Stress - drug effects Review Stroke Toxicity Traumatic brain injury
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