Alcohol Abstinence Does Not Fully Reverse Abnormalities of Mucosal-Associated Invariant T Cells in the Blood of Patients With Alcoholic Hepatitis

Alcoholic hepatitis (AH) develops in approximately 30% of chronic heavy drinkers. The immune system of patients with AH is hyperactivated, yet ineffective against infectious diseases. Mucosal-associated invariant T (MAIT) cells are innate-like lymphocytes that are highly enriched in liver, mucosa, a...

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Veröffentlicht in:	Clinical and translational gastroenterology 2019-06, Vol.10 (6), p.e00052
Hauptverfasser:	Li, Wei, Lin, Edward L, Liangpunsakul, Suthat, Lan, Jie, Chalasani, Sai, Rane, Sushmita, Puri, Puneet, Kamath, Patrick S, Sanyal, Arun J, Shah, Vijay H, Radaeva, Svetlana, Crabb, David W, Chalasani, Naga, Yu, Qigui
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Alcohol Abstinence Biomarkers - blood Case-Control Studies Cytokines - blood Female Flow Cytometry Hepatitis, Alcoholic - blood Hepatitis, Alcoholic - immunology HLA-DR Antigens - blood Humans Interleukin-18 - blood Male Middle Aged Mucosal-Associated Invariant T Cells - immunology
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