The MTOR signaling pathway regulates macrophage differentiation from mouse myeloid progenitors by inhibiting autophagy

Understanding of the mechanism for myeloid differentiation provides important insights into the hematopoietic developmental processes. By using an ESC-derived myeloid progenitor cell model, we found that CSF2/GM-CSF triggered macrophage differentiation and activation of the MTOR signaling pathway. A...

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Veröffentlicht in:	Autophagy 2019-07, Vol.15 (7), p.1150-1162
Hauptverfasser:	Zhang, Meichao, Liu, Furao, Zhou, Pingting, Wang, Qian, Xu, Ci, Li, Yanyan, Bian, Lei, Liu, Yuanhua, Zhou, Jiaxi, Wang, Fei, Yao, Yuan, Fang, Yong, Li, Dong
Format:	Artikel
Sprache:	eng
Schlagworte:	Autophagy CSF2 MTOR myeloid differentiation myeloid progenitors Research Paper - Basic Science
Online-Zugang:	Volltext
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