Association of Schizophrenia Risk With Disordered Niacin Metabolism in an Indian Genome-wide Association Study

IMPORTANCE: Genome-wide association studies (GWASs) in European populations have identified more than 100 schizophrenia-associated loci. A schizophrenia GWAS in a unique Indian population offers novel findings. OBJECTIVE: To discover and functionally evaluate genetic loci for schizophrenia in a GWAS...

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Veröffentlicht in:	JAMA psychiatry (Chicago, Ill.) Ill.), 2019-10, Vol.76 (10), p.1026-1034
Hauptverfasser:	Periyasamy, Sathish, John, Sujit, Padmavati, Raman, Rajendren, Preeti, Thirunavukkarasu, Priyadarshini, Gratten, Jacob, Vinkhuyzen, Anna, McRae, Allan, Holliday, Elizabeth G, Nyholt, Dale R, Nancarrow, Derek, Bakshi, Andrew, Hemani, Gibran, Nertney, Deborah, Smith, Heather, Filippich, Cheryl, Patel, Kalpana, Fowdar, Javed, McLean, Duncan, Tirupati, Srinivasan, Nagasundaram, Arunkumar, Gundugurti, Prasad Rao, Selvaraj, Krishnamurthy, Jegadeesan, Jayaprakash, Jorde, Lynn B, Wray, Naomi R, Brown, Matthew A, Suetani, Rachel, Giacomotto, Jean, Thara, Rangaswamy, Mowry, Bryan J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Animals Case-Control Studies Cell Line, Tumor Chromosomes, Human, Pair 8 - genetics Disease Models, Animal Family Female Gene expression Genetic Predisposition to Disease - genetics Genetic Techniques Genome-Wide Association Study Genomes Humans India Male Metabolism Middle Aged Niacin - metabolism Online First Original Investigation Pentosyltransferases - genetics Polymorphism, Single Nucleotide Psychosis Schizophrenia Schizophrenia - genetics Zebrafish
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