Osteoblastic lysosome plays a central role in mineralization

Mineralization is the most fundamental process in vertebrates. It is predominantly mediated by osteoblasts, which secrete mineral precursors, most likely through matrix vesicles (MVs). These vesicular structures are calcium and phosphate rich and contain organic material such as acidic proteins. How...

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Veröffentlicht in:	Science advances 2019-07, Vol.5 (7), p.eaax0672-eaax0672
Hauptverfasser:	Iwayama, Tomoaki, Okada, Tomoko, Ueda, Tsugumi, Tomita, Kiwako, Matsumoto, Shuji, Takedachi, Masahide, Wakisaka, Satoshi, Noda, Takeshi, Ogura, Taku, Okano, Tomomichi, Fratzl, Peter, Ogura, Toshihiko, Murakami, Shinya
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Biology SciAdv r-articles
Online-Zugang:	Volltext
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