H3.3 Barcoding of Nucleus Accumbens Transcriptional Activity Identifies Novel Molecular Cascades Associated with Cocaine Self-administration in Mice

Although numerous epigenetic modifications have been associated with addiction, little work has explored the turnover of histone variants. Uniquely, the H3.3 variant incorporates stably and preferentially into chromatin independently of DNA replication at active sites of transcription and transcript...

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Veröffentlicht in:The Journal of neuroscience 2019-07, Vol.39 (27), p.5247-5254
Hauptverfasser: Wimmer, Mathieu E, Fant, Bruno, Swinford-Jackson, Sarah E, Testino, Alexander, Van Nest, Duncan, Abel, Ted, Pierce, R Christopher
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Sprache:eng
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