Glucose Induces Slow-Wave Sleep by Exciting the Sleep-Promoting Neurons in the Ventrolateral Preoptic Nucleus: A New Link between Sleep and Metabolism

Sleep-active neurons located in the ventrolateral preoptic nucleus (VLPO) play a crucial role in the induction and maintenance of slow-wave sleep (SWS). However, the cellular and molecular mechanisms responsible for their activation at sleep onset remain poorly understood. Here, we test the hypothes...

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Veröffentlicht in:	The Journal of neuroscience 2015-07, Vol.35 (27), p.9900-9911
Hauptverfasser:	Varin, Christophe, Rancillac, Armelle, Geoffroy, Hélène, Arthaud, Sébastien, Fort, Patrice, Gallopin, Thierry
Format:	Artikel
Sprache:	eng
Schlagworte:	Action Potentials - drug effects Action Potentials - physiology Adrenergic alpha-Agonists - pharmacology Animals Brain Waves - drug effects Coumaric Acids - pharmacology Deoxyglucose - pharmacology Gene Expression Regulation - drug effects Glucose - pharmacology Glucose Transporter Type 3 - genetics Glucose Transporter Type 3 - metabolism In Vitro Techniques Life Sciences Male Membrane Transport Modulators - pharmacology Mice Mice, Inbred C57BL Neurons - drug effects Neurons and Cognition Norepinephrine - pharmacology Preoptic Area - cytology Preoptic Area - metabolism Proto-Oncogene Proteins c-fos - metabolism Sleep - drug effects Sweetening Agents - pharmacology
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