Intrahippocampal Anisomycin Impairs Spatial Performance on the Morris Water Maze

New memories are thought to be solidified (consolidated) by de novo synthesis of proteins in the period subsequent to learning. This view stems from the observation that protein synthesis inhibitors, such as anisomycin (ANI), administered during this consolidation period cause memory impairments. Ho...

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Veröffentlicht in:	The Journal of neuroscience 2015-08, Vol.35 (31), p.11118-11124
Hauptverfasser:	Dubue, Jonathan D, McKinney, Ty L, Treit, Dallas, Dickson, Clayton T
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anisomycin - pharmacology Hippocampus - drug effects Male Maze Learning - drug effects Protein Synthesis Inhibitors - pharmacology Rats Rats, Sprague-Dawley Sodium Channel Blockers - pharmacology Spatial Behavior - drug effects Tetrodotoxin - pharmacology
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