Oligophrenin-1 Connects Exocytotic Fusion to Compensatory Endocytosis in Neuroendocrine Cells

Oligophrenin-1 (OPHN1) is a protein with multiple domains including a Rho family GTPase-activating (Rho-GAP) domain, and a Bin-Amphiphysin-Rvs (BAR) domain. Involved in X-linked intellectual disability, OPHN1 has been reported to control several synaptic functions, including synaptic plasticity, syn...

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Veröffentlicht in:	The Journal of neuroscience 2015-08, Vol.35 (31), p.11045-11055
Hauptverfasser:	Houy, Sébastien, Estay-Ahumada, Catherine, Croisé, Pauline, Calco, Valérie, Haeberlé, Anne-Marie, Bailly, Yannick, Billuart, Pierre, Vitale, Nicolas, Bader, Marie-France, Ory, Stéphane, Gasman, Stéphane
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cattle Cell Membrane - metabolism Chromaffin Cells - metabolism Cytoskeletal Proteins - metabolism Endocytosis - physiology Exocytosis - physiology GTPase-Activating Proteins - metabolism Life Sciences Membrane Fusion - physiology Mice Mice, Knockout Neurons and Cognition Nuclear Proteins - metabolism Synaptic Vesicles - metabolism
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