MSX3 Switches Microglia Polarization and Protects from Inflammation-Induced Demyelination

The major challenge for progressive multiple sclerosis therapy is the promotion of remyelination from inflammation-induced demyelination. A switch from an M1- to an M2-dominant polarization of microglia is critical in these repair processes. In this study, we identified the homeobox gene msh-like ho...

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Veröffentlicht in:The Journal of neuroscience 2015-04, Vol.35 (16), p.6350-6365
Hauptverfasser: Yu, Zhongwang, Sun, Dingya, Feng, Jifeng, Tan, Weixing, Fang, Xue, Zhao, Ming, Zhao, Xiaolin, Pu, Yingyan, Huang, Aijun, Xiang, Zhenghua, Cao, Li, He, Cheng
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Sprache:eng
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