Single-cell analyses identify distinct and intermediate states of zebrafish pancreatic islet development

Abstract Pancreatic endocrine islets are vital for glucose homeostasis. However, the islet developmental trajectory and its regulatory network are not well understood. To define the features of these specification and differentiation processes, we isolated individual islet cells from TgBAC(neurod1:E...

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Veröffentlicht in:	Journal of molecular cell biology 2019-06, Vol.11 (6), p.435-447
Hauptverfasser:	Lu, Chong-Jian, Fan, Xiao-Ying, Guo, Yue-Feng, Cheng, Zhen-Chao, Dong, Ji, Chen, Jin-Zi, Li, Lian-Yan, Wang, Mei-Wen, Wu, Ze-Kai, Wang, Fei, Tong, Xiang-Jun, Luo, Ling-Fei, Tang, Fu-Chou, Zhu, Zuo-Yan, Zhang, Bo
Format:	Artikel
Sprache:	eng
Schlagworte:	Editor's Choice Original
Online-Zugang:	Volltext
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