miR-25 Promotes Cell Proliferation, Migration, and Invasion of Non-Small-Cell Lung Cancer by Targeting the LATS2/YAP Signaling Pathway

Metastasis is the leading cause of high mortality in lung cancer patients, and metastatic lung cancer is difficult to treat. miRNAs are involved in various biological processes of cancer, including metastasis. Our previous studies revealed that miR-25 promoted non-small-cell lung cancer (NSCLC) cell...

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Veröffentlicht in:	Oxidative medicine and cellular longevity 2019, Vol.2019 (2019), p.1-14
Hauptverfasser:	Ning, Yong, Li, Yong, Lu, Zhongxin, Yan, Ge, Zheng, Chao, Liu, Shuiyi, Li, Xiaoyi, Jiang, Liyuan, Zhang, Tianzhu, Hu, Hui, Wu, Tangwei, Chen, Weiqun
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptor Proteins, Signal Transducing - genetics Adaptor Proteins, Signal Transducing - metabolism Apoptosis Biomarkers Cancer Cancer therapies Carcinoma, Non-Small-Cell Lung - genetics Carcinoma, Non-Small-Cell Lung - metabolism Carcinoma, Non-Small-Cell Lung - pathology Cell cycle Cell growth Cell Line, Tumor Cell Proliferation - genetics Cell Proliferation - physiology China Gene expression Gene Expression Regulation, Neoplastic Genetic aspects Genomes Health aspects Humans Kinases Lung cancer Lung cancer, Non-small cell Lung Neoplasms - genetics Lung Neoplasms - metabolism Lung Neoplasms - pathology Medical prognosis Metastasis MicroRNA MicroRNAs - genetics MicroRNAs - metabolism Mortality Oxidative stress Pathogenesis Prostate Protein-Serine-Threonine Kinases - genetics Protein-Serine-Threonine Kinases - metabolism Signal Transduction Survival analysis Transcription Factors - genetics Transcription Factors - metabolism Tumor proteins Tumor Suppressor Proteins - genetics Tumor Suppressor Proteins - metabolism
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