Airway Smooth Muscle-Specific Transcriptomic Signatures of Glucocorticoid Exposure

Glucocorticoids, commonly used asthma controller medications, decrease symptoms in most patients, but some remain symptomatic despite high-dose treatment. The physiological basis underlying the glucocorticoid response, especially in asthma patients with severe, refractory disease, is not fully under...

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Veröffentlicht in:American journal of respiratory cell and molecular biology 2019-07, Vol.61 (1), p.110-120
Hauptverfasser: Kan, Mengyuan, Koziol-White, Cynthia, Shumyatcher, Maya, Johnson, Martin, Jester, William, Panettieri, Jr, Reynold A, Himes, Blanca E
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Sprache:eng
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