Development of Staphylococcus aureus tolerance to antimicrobial photodynamic inactivation and antimicrobial blue light upon sub-lethal treatment

Antimicrobial photodynamic inactivation (aPDI) and antimicrobial blue light (aBL) are considered low-risk treatments for the development of bacterial resistance and/or tolerance due to their multitargeted modes of action. In this study, we assessed the development of Staphylococcus aureus tolerance...

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Veröffentlicht in:	Scientific reports 2019-07, Vol.9 (1), p.9423-18, Article 9423
Hauptverfasser:	Rapacka-Zdonczyk, Aleksandra, Wozniak, Agata, Pieranski, Michal, Woziwodzka, Anna, Bielawski, Krzysztof P., Grinholc, Mariusz
Format:	Artikel
Sprache:	eng
Schlagworte:	45/70 631/326/22/1434 692/499 692/699/255/1318 Anti-Bacterial Agents - pharmacology Antimicrobial agents Bacterial Proteins - genetics DNA-directed DNA polymerase DNA-Directed DNA Polymerase - genetics Doxycycline Drug resistance Drug Resistance, Bacterial - drug effects Gentamicin Humanities and Social Sciences Inactivation Light Methicillin-Resistant Staphylococcus aureus - drug effects Microbial Sensitivity Tests multidisciplinary Mutation Mutation rates Photosensitization Photosensitizing Agents - pharmacology Porphyrins Porphyrins - pharmacology RecA protein Rifampin Rifampin - pharmacology Rose Bengal - pharmacology Science Science (multidisciplinary) Staphylococcus aureus Staphylococcus aureus - drug effects Staphylococcus aureus - genetics Streptococcus infections
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