Single cell transcriptomics reveals spatial and temporal dynamics of gene expression in the developing mouse spinal cord

The coordinated spatial and temporal regulation of gene expression in the vertebrate neural tube determines the identity of neural progenitors and the function and physiology of the neurons they generate. Progress has been made deciphering the gene regulatory programmes that are responsible for this...

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Veröffentlicht in:	Development (Cambridge) 2019-03, Vol.146 (12)
Hauptverfasser:	Delile, Julien, Rayon, Teresa, Melchionda, Manuela, Edwards, Amelia, Briscoe, James, Sagner, Andreas
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Differentiation - genetics Cluster Analysis Female Gene Expression Profiling Gene Expression Regulation, Developmental Gene Regulatory Networks Interneurons - metabolism Male Mice Neural Tube - embryology Neurons - metabolism Organogenesis RNA, Messenger - metabolism Single-Cell Analysis Spinal Cord - embryology Time Factors Transcription Factors - metabolism Transcriptome
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