Inhibitory Effects of a Novel Chrysin-Derivative, CPD 6, on Acute and Chronic Skin Inflammation

The skin is an important physiological barrier against external stimuli, such as ultraviolet radiation (UV), xenobiotics, and bacteria. Dermal inflammatory reactions are associated with various skin disorders, including chemical-induced irritation and atopic dermatitis. Modulation of skin inflammato...

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Veröffentlicht in:	International journal of molecular sciences 2019-05, Vol.20 (11), p.2607
Hauptverfasser:	Yu, Chan-Hee, Suh, Beomseon, Shin, Iljin, Kim, Eun-Hye, Kim, Donghyun, Shin, Young-Jun, Chang, Sun-Young, Baek, Seung-Hoon, Kim, Hyoungsu, Bae, Ok-Nam
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models Anti-inflammatory agents Atopic dermatitis Chemical compounds Chemical reactions External stimuli Inflammation Inflammatory response Irritation Janus kinase 2 Keratinocytes Kinases Lipopolysaccharides Macrophages NF-κB protein Nitric oxide Organic chemistry Pharmacology Rodents Signal transduction Skin diseases Stat1 protein Tumor necrosis factor-TNF Tumor necrosis factor-α Ultraviolet radiation Xenobiotics γ-Interferon
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