Human cytomegalovirus infection dysregulates neural progenitor cell fate by disrupting Hes1 rhythm and down-regulating its expression

Human cytomegalovirus(HCMV) infection is a leading cause of birth defects, primarily affecting the central nervous system and causing its maldevelopment. As the essential downstream effector of Notch signaling pathway, Hes1, and its dynamic expression, plays an essential role on maintaining neural p...

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Veröffentlicht in:Virologica Sinica 2017-06, Vol.32 (3), p.188-198
Hauptverfasser: Liu, Xi-Juan, Jiang, Xuan, Huang, Sheng-Nan, Sun, Jin-Yan, Zhao, Fei, Zeng, Wen-Bo, Luo, Min-Hua
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Sprache:eng
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