Skin Carotenoid Index in a large Japanese population sample
Carotenoids are anti-oxidative agents. Human skin and eyes contain specific carotenoid species known to prevent various pathologies caused by oxidative stress. We quantified skin and eye carotenoid levels and investigated their potential correlation in a population including 985 Japanese patients an...
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| Veröffentlicht in: | Scientific reports 2019-06, Vol.9 (1), p.9318-9, Article 9318 |
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| creator | Obana, Akira Gohto, Yuko Gellermann, Werner Ermakov, Igor V. Sasano, Hiroyuki Seto, Takahiko Bernstein, Paul S. |
| description | Carotenoids are anti-oxidative agents. Human skin and eyes contain specific carotenoid species known to prevent various pathologies caused by oxidative stress. We quantified skin and eye carotenoid levels and investigated their potential correlation in a population including 985 Japanese patients and staff members of an ophthalmology clinic (577 men, 408 women, mean age of 69.7 ± 13.6 [SD]). Skin carotenoid (SC) and macular pigment (MP) levels were measured with reflection spectroscopy and autofluorescence imaging methods, respectively. The mean SC index was 343.1 ± 142.1 (SD). SC indices for women were higher than for men (382 vs 315, p |
| doi_str_mv | 10.1038/s41598-019-45751-6 |
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Human skin and eyes contain specific carotenoid species known to prevent various pathologies caused by oxidative stress. We quantified skin and eye carotenoid levels and investigated their potential correlation in a population including 985 Japanese patients and staff members of an ophthalmology clinic (577 men, 408 women, mean age of 69.7 ± 13.6 [SD]). Skin carotenoid (SC) and macular pigment (MP) levels were measured with reflection spectroscopy and autofluorescence imaging methods, respectively. The mean SC index was 343.1 ± 142.1 (SD). SC indices for women were higher than for men (382 vs 315, p < 0.001). Smokers and overweight subjects (BMI ≥ 25) had lower SC indices. Subjects taking lutein supplements had higher SC indices than non-supplementing subjects (415 vs 325, p < 0.001). SC and MP indices were significantly correlated. The obtained data set can be used for reference purposes by Japanese subjects and researchers interested in tissue responses to diets high in carotenoids and lutein supplementation.</description><identifier>ISSN: 2045-2322</identifier><identifier>EISSN: 2045-2322</identifier><identifier>DOI: 10.1038/s41598-019-45751-6</identifier><identifier>PMID: 31249340</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>140/125 ; 639/624/1020 ; 692/53/2421 ; 692/700/2814 ; Adolescent ; Adult ; Aged ; Aged, 80 and over ; Body weight ; Carotenoids ; Carotenoids - analysis ; Databases, Factual ; Dietary supplements ; Female ; Humanities and Social Sciences ; Humans ; Japan ; Male ; Middle Aged ; multidisciplinary ; Overweight ; Oxidative stress ; Science ; Science (multidisciplinary) ; Skin ; Skin - chemistry ; Spectroscopy ; Young Adult</subject><ispartof>Scientific reports, 2019-06, Vol.9 (1), p.9318-9, Article 9318</ispartof><rights>The Author(s) 2019</rights><rights>2019. 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Human skin and eyes contain specific carotenoid species known to prevent various pathologies caused by oxidative stress. We quantified skin and eye carotenoid levels and investigated their potential correlation in a population including 985 Japanese patients and staff members of an ophthalmology clinic (577 men, 408 women, mean age of 69.7 ± 13.6 [SD]). Skin carotenoid (SC) and macular pigment (MP) levels were measured with reflection spectroscopy and autofluorescence imaging methods, respectively. The mean SC index was 343.1 ± 142.1 (SD). SC indices for women were higher than for men (382 vs 315, p < 0.001). Smokers and overweight subjects (BMI ≥ 25) had lower SC indices. Subjects taking lutein supplements had higher SC indices than non-supplementing subjects (415 vs 325, p < 0.001). SC and MP indices were significantly correlated. The obtained data set can be used for reference purposes by Japanese subjects and researchers interested in tissue responses to diets high in carotenoids and lutein supplementation.</description><subject>140/125</subject><subject>639/624/1020</subject><subject>692/53/2421</subject><subject>692/700/2814</subject><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Body weight</subject><subject>Carotenoids</subject><subject>Carotenoids - analysis</subject><subject>Databases, Factual</subject><subject>Dietary supplements</subject><subject>Female</subject><subject>Humanities and Social Sciences</subject><subject>Humans</subject><subject>Japan</subject><subject>Male</subject><subject>Middle Aged</subject><subject>multidisciplinary</subject><subject>Overweight</subject><subject>Oxidative stress</subject><subject>Science</subject><subject>Science (multidisciplinary)</subject><subject>Skin</subject><subject>Skin - chemistry</subject><subject>Spectroscopy</subject><subject>Young Adult</subject><issn>2045-2322</issn><issn>2045-2322</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>C6C</sourceid><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp9kUuP0zAUhS0EolWZP8ACRZoNm8D1M7aQRhpVPIoqsQDWlpPYnXRSO2Mno-Hf45KhFBZ4Y8v3u-f6-CD0EsMbDFS-TQxzJUvAqmS84rgUT9CSAOMloYQ8PTsv0EVKe8iLE8Wweo4WFBOmKIMlevf1tvPF2sQwWh-6ttj41j4U-c4UvYk7W3w2g_E22WIIw9SbsQu-SOYw9PYFeuZMn-zF475C3z-8_7b-VG6_fNysr7dlw6Ucy7Z1jrZGKCkwd620vBZSOlxJblgtaM3ACmPqSiqQFXUOGCgM4EAxAS2lK3Q16w5TfbBtY_0YTa-H2B1M_KGD6fTfFd_d6F2414Krqsq_tUKvHwViuJtsGvWhS43t-2wsTEkTwkEQqOQRvfwH3Ycp-mwvU0xSziuJM0VmqokhpWjd6TEY9DEePcejczz6Vzxa5KZX5zZOLb_DyACdgZRLfmfjn9n_kf0JV7GZrQ</recordid><startdate>20190627</startdate><enddate>20190627</enddate><creator>Obana, Akira</creator><creator>Gohto, Yuko</creator><creator>Gellermann, Werner</creator><creator>Ermakov, Igor V.</creator><creator>Sasano, Hiroyuki</creator><creator>Seto, Takahiko</creator><creator>Bernstein, Paul S.</creator><general>Nature Publishing Group UK</general><general>Nature Publishing Group</general><scope>C6C</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>88I</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-4228-7666</orcidid></search><sort><creationdate>20190627</creationdate><title>Skin Carotenoid Index in a large Japanese population sample</title><author>Obana, Akira ; 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Human skin and eyes contain specific carotenoid species known to prevent various pathologies caused by oxidative stress. We quantified skin and eye carotenoid levels and investigated their potential correlation in a population including 985 Japanese patients and staff members of an ophthalmology clinic (577 men, 408 women, mean age of 69.7 ± 13.6 [SD]). Skin carotenoid (SC) and macular pigment (MP) levels were measured with reflection spectroscopy and autofluorescence imaging methods, respectively. The mean SC index was 343.1 ± 142.1 (SD). SC indices for women were higher than for men (382 vs 315, p < 0.001). Smokers and overweight subjects (BMI ≥ 25) had lower SC indices. Subjects taking lutein supplements had higher SC indices than non-supplementing subjects (415 vs 325, p < 0.001). SC and MP indices were significantly correlated. The obtained data set can be used for reference purposes by Japanese subjects and researchers interested in tissue responses to diets high in carotenoids and lutein supplementation.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>31249340</pmid><doi>10.1038/s41598-019-45751-6</doi><tpages>9</tpages><orcidid>https://orcid.org/0000-0002-4228-7666</orcidid><oa>free_for_read</oa></addata></record> |
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| subjects | 140/125 639/624/1020 692/53/2421 692/700/2814 Adolescent Adult Aged Aged, 80 and over Body weight Carotenoids Carotenoids - analysis Databases, Factual Dietary supplements Female Humanities and Social Sciences Humans Japan Male Middle Aged multidisciplinary Overweight Oxidative stress Science Science (multidisciplinary) Skin Skin - chemistry Spectroscopy Young Adult |
| title | Skin Carotenoid Index in a large Japanese population sample |
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