Detailed Dendritic Excitatory/Inhibitory Balance through Heterosynaptic Spike-Timing-Dependent Plasticity

The balance between excitatory and inhibitory inputs is a key feature of cortical dynamics. Such a balance is arguably preserved in dendritic branches, yet its underlying mechanism and functional roles remain unknown. In this study, we developed computational models of heterosynaptic spike-timing-de...

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Veröffentlicht in:	The Journal of neuroscience 2017-12, Vol.37 (50), p.12106-12122
Hauptverfasser:	Hiratani, Naoki, Fukai, Tomoki
Format:	Artikel
Sprache:	eng
Schlagworte:	Action Potentials - physiology Animals CA1 Region, Hippocampal - cytology CA1 Region, Hippocampal - physiology Calcium Signaling - physiology Computation Computational neuroscience Computer Simulation Corpus Striatum - cytology Corpus Striatum - physiology Cortex Critical period Dendrites - physiology Dendritic plasticity Dendritic structure Firing pattern gamma-Aminobutyric Acid - physiology Glutamatergic transmission Learning - physiology Mice Models, Neurological Neuronal Plasticity - physiology Neurons Plastic properties Plasticity Rats Synapses Synapses - classification Synapses - physiology Synaptic plasticity Synaptogenesis Time Factors γ-Aminobutyric acid
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