Drosophila Exo70 Is Essential for Neurite Extension and Survival under Thermal Stress

The octomeric exocyst complex governs the final step of exocytosis in both plants and animals. Its roles, however, extend beyond exocytosis and include organelle biogenesis, ciliogenesis, cell migration, and cell growth. Exo70 is a conserved component of the exocyst whose function in is unclear. In...

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Veröffentlicht in:	The Journal of neuroscience 2018-09, Vol.38 (37), p.8071-8086
Hauptverfasser:	Koon, Alex Chun, Chen, Zhefan Stephen, Peng, Shaohong, Fung, Joyce Man See, Zhang, Xiaoman, Lembke, Kayly M, Chow, Hoi Kin, Frank, C Andrew, Jiang, Liwen, Lau, Kwok-Fai, Chan, Ho Yin Edwin
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Genetically Modified Axonogenesis Cell adhesion & migration Cell Membrane - metabolism Cell migration Cell surface Cell Survival - genetics Drosophila Drosophila Proteins - genetics Drosophila Proteins - metabolism Environmental changes Exocytosis Exocytosis - physiology Glutamic acid receptors Guanosine triphosphatases Hot Temperature Insects Lethality Locomotor activity Membrane proteins Motor neurons Mutants Neurites - metabolism Neuromuscular Junction - genetics Neuromuscular Junction - metabolism Neuromuscular junctions Neuronal Outgrowth - genetics Neurons - metabolism Octopamine Phenotypes Protein transport Proteins Receptor density Starvation Stress, Physiological - genetics Survival Synaptogenesis Thermal stress Transport buildings, stations and terminals Vesicular Transport Proteins - genetics Vesicular Transport Proteins - metabolism
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