Anti-cancer effects of chemotherapeutic agent; 17-AAG, in combined with gold nanoparticles and irradiation in human colorectal cancer cells

Objective The present study evaluated the anti-cancer effects of irradiation (Ir) alone, Ir after heat shock protein 90 inhibitor; 17-allylamino-17-demethoxygeldanamycin (17-AAG) and gold nanoparticle (GNP) treatments in human colorectal cancer cell line (HCT-116), with the targeting of related mech...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Daru 2019-06, Vol.27 (1), p.111-119
Hauptverfasser:	Moradi, Zhino, Mohammadian, Mahshid, Saberi, Hassan, Ebrahimifar, Meysam, Mohammadi, Zeinab, Ebrahimpour, Mahnaz, Behrouzkia, Zhaleh
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Antineoplastic Combined Chemotherapy Protocols - pharmacology Apoptosis Benzoquinones - pharmacology Biomedical and Life Sciences Biomedicine Cancer cells Cancer treatment Caspase 3 - metabolism Cell Survival - drug effects Cell Survival - radiation effects Chemoradiotherapy Chemotherapy Colorectal cancer Colorectal Neoplasms - drug therapy Colorectal Neoplasms - metabolism Colorectal Neoplasms - radiotherapy DNA DNA damage Dose-Response Relationship, Drug Drug therapy Electrophoresis Gene Expression Regulation, Neoplastic - drug effects Gene Expression Regulation, Neoplastic - radiation effects Gold - pharmacology HCT116 Cells Heat shock proteins Humans Lactams, Macrocyclic - pharmacology Medicinal Chemistry Metal Nanoparticles Nanoparticles Pharmaceutical Sciences/Technology Pharmacology/Toxicology Radiation (Physics) Research Article Up-Regulation
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!