Agonist‐induced desensitisation of β3‐adrenoceptors: Where, when, and how?

β3‐Adrenoceptor agonists have proven useful in the treatment of overactive bladder syndrome, but it is not known whether their efficacy during chronic administration may be limited by receptor‐induced desensitisation. Whereas the β2‐adrenoceptor has phosphorylation sites that are important for desen...

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Veröffentlicht in:	British journal of pharmacology 2019-07, Vol.176 (14), p.2539-2558
Hauptverfasser:	Okeke, Katerina, Angers, Stephane, Bouvier, Michel, Michel, Martin C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic receptors Agonists Comparative studies Desensitization mRNA Phosphorylation Receptors (physiology) Review Themed Section: Review Urinary bladder
Online-Zugang:	Volltext
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