Tail domains of myosin-1e regulate phosphatidylinositol signaling and F-actin polymerization at the ventral layer of podosomes
During podosome formation, distinct phosphatidylinositol 3,4,5-trisphosphate lipid (PI(3,4,5)P3) production and F-actin polymerization take place at integrin-mediated adhesions. Membrane-associated actin regulation factors, such as myosin-1, serve as key molecules to link phosphatidylinositol signal...
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Veröffentlicht in: | Molecular biology of the cell 2019-03, Vol.30 (5), p.622-635 |
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Hauptverfasser: | , , , , , , |
Format: | Artikel |
Sprache: | eng |
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