Tail domains of myosin-1e regulate phosphatidylinositol signaling and F-actin polymerization at the ventral layer of podosomes

During podosome formation, distinct phosphatidylinositol 3,4,5-trisphosphate lipid (PI(3,4,5)P3) production and F-actin polymerization take place at integrin-mediated adhesions. Membrane-associated actin regulation factors, such as myosin-1, serve as key molecules to link phosphatidylinositol signal...

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Veröffentlicht in:Molecular biology of the cell 2019-03, Vol.30 (5), p.622-635
Hauptverfasser: Zhang, Yage, Cao, Fakun, Zhou, Yuhuan, Feng, Zhen, Sit, Brian, Krendel, Mira, Yu, Cheng-Han
Format: Artikel
Sprache:eng
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