Pharmacologic targeting of β-catenin improves fracture healing in old mice

β-catenin protein needs to be precisely regulated for effective fracture repair. The pace of fracture healing slows with age, associated with a transient increase in β-catenin during the initial phase of the repair process. Here we examined the ability of pharmacologic agents that target β-catenin t...

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Veröffentlicht in:Scientific reports 2019-06, Vol.9 (1), p.9005-9, Article 9005
Hauptverfasser: Kwak, Yoon Hae, Barrientos, Tomasa, Furman, Bridgette, Zhang, Hazel, Puviindran, Vijitha, Cutcliffe, Hattie, Herfarth, Jonas, Nwankwo, Eugene, Alman, Benjamin A.
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