Tumor suppressors BTG1 and BTG2: Beyond growth control

Since the identification of B‐cell translocation gene 1 (BTG1) and BTG2 as antiproliferation genes more than two decades ago, their protein products have been implicated in a variety of cellular processes including cell division, DNA repair, transcriptional regulation and messenger RNA stability. In...

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Veröffentlicht in:	Journal of cellular physiology 2019-05, Vol.234 (5), p.5379-5389
Hauptverfasser:	Yuniati, Laurensia, Scheijen, Blanca, Meer, Laurens T., Leeuwen, Frank N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals antiproliferation BTG1 BTG2 BTG2 protein B‐cell malignancies Cancer Cell Cycle Cell Differentiation Cell division Cell Proliferation Deoxyribonucleic acid Deregulation DNA DNA repair Gene Expression Regulation, Neoplastic Gene regulation Genes Genotoxicity Hematopoiesis Homeostasis Humans Immediate-Early Proteins - genetics Immediate-Early Proteins - metabolism Leukemia Lymphocytes B Lymphoma Mini‐review Mini‐reviews Molecular modelling mRNA stability Neoplasm Proteins - genetics Neoplasm Proteins - metabolism Neoplasms - genetics Neoplasms - metabolism Neoplasms - pathology Proteins Ribonucleic acid RNA Signal Transduction Solid tumors Suppressors Transcription Transcription, Genetic Translocation tumor suppressor Tumor Suppressor Proteins - genetics Tumor Suppressor Proteins - metabolism Tumors
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