Prophylactic incisional negative pressure wound therapy reduces the risk of surgical site infection after caesarean section in obese women: a pragmatic randomised clinical trial
Objective To evaluate the reduction of surgical site infections by prophylactic incisional negative pressure wound therapy compared with standard postoperative dressings in obese women giving birth by caesarean section. Design Multicentre randomised controlled trial. Setting Five hospitals in Denmar...
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| Veröffentlicht in: | BJOG : an international journal of obstetrics and gynaecology 2019-04, Vol.126 (5), p.628-635 |
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| creator | Hyldig, N Vinter, CA Kruse, M Mogensen, O Bille, C Sorensen, JA Lamont, RF Wu, C Heidemann, LN Ibsen, MH Laursen, JB Ovesen, PG Rorbye, C Tanvig, M Joergensen, JS |
| description | Objective
To evaluate the reduction of surgical site infections by prophylactic incisional negative pressure wound therapy compared with standard postoperative dressings in obese women giving birth by caesarean section.
Design
Multicentre randomised controlled trial.
Setting
Five hospitals in Denmark.
Population
Obese women (prepregnancy body mass index (BMI) ≥30 kg/m2) undergoing elective or emergency caesarean section.
Method
The participants were randomly assigned to incisional negative pressure wound therapy or a standard dressing after caesarean section and analysed by intention‐to‐treat. Blinding was not possible due to the nature of the intervention.
Main outcome measures
The primary outcome was surgical site infection requiring antibiotic treatment within the first 30 days after surgery. Secondary outcomes included wound exudate, dehiscence and health‐related quality of life.
Results
Incisional negative pressure wound therapy was applied to 432 women and 444 women had a standard dressing. Demographics were similar between groups. Surgical site infection occurred in 20 (4.6%) women treated with incisional negative pressure wound therapy and in 41 (9.2%) women treated with a standard dressing (relative risk 0.50, 95% CI 0.30–0.84; number needed to treat 22; P = 0.007). The effect remained statistically significant when adjusted for BMI and other potential risk factors. Incisional negative pressure wound therapy significantly reduced wound exudate whereas no difference was found for dehiscence and quality of life between the two groups.
Conclusion
Prophylactic use of incisional negative pressure wound therapy reduced the risk of surgical site infection in obese women giving birth by caesarean section.
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RCT: prophylactic incisional NPWT versus standard dressings postcaesarean in 876 women significantly reduces the risk of SSI.
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RCT: prophylactic incisional NPWT versus standard dressings postcaesarean in 876 women significantly reduces the risk of SSI. |
| doi_str_mv | 10.1111/1471-0528.15413 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6586160</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2187715398</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4673-fa89cf8fa58ef427849019775eca5634bd65040195f2c4a211f2201194b597663</originalsourceid><addsrcrecordid>eNqFks2P1CAYhxujcdfVszdD4sVLd6F8tPVgsm78zCbrQc_kHfoyw9pChXY382f5H0pnxol6kQvw8vAA-VEUzxk9Z7ldMFGzksqqOWdSMP6gOD1WHu7GtKS8ak6KJyndUspURfnj4oRTqpSQ4rT4-SWGcbPtwUzOEOeNSy546InHNUzuDskYMaU5IrkPs-_ItMEI45ZE7GaDaZmT6NJ3EizJ2NqZvDm5CbPMYrYGT8BOGIkBTBARPEmHuvMkrDAt6gH9awL5MFgPsFwlgu_C4BJ2xPTO77RTdNA_LR5Z6BM-O_Rnxbf3775efSyvbz58urq8Lo1QNS8tNK2xjQXZoBVV3YiWsrauJRqQiotVpyQVuSRtZQRUjNmqooy1YiXbWil-VrzZe8d5NWBn0E8Rej1GN0Dc6gBO_73i3Uavw51WslFM0Sx4dRDE8GPGNOn8HIN9Dx7DnHRFmxwal5xl9OU_6G2YY44hU6ypayZ522TqYk-ZGFKKaI-XYVQv30Ev4eslfL37DnnHiz_fcOR_558BuQfuXY_b__n02883e_EvzTzDHA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2187715398</pqid></control><display><type>article</type><title>Prophylactic incisional negative pressure wound therapy reduces the risk of surgical site infection after caesarean section in obese women: a pragmatic randomised clinical trial</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>Hyldig, N ; Vinter, CA ; Kruse, M ; Mogensen, O ; Bille, C ; Sorensen, JA ; Lamont, RF ; Wu, C ; Heidemann, LN ; Ibsen, MH ; Laursen, JB ; Ovesen, PG ; Rorbye, C ; Tanvig, M ; Joergensen, JS</creator><creatorcontrib>Hyldig, N ; Vinter, CA ; Kruse, M ; Mogensen, O ; Bille, C ; Sorensen, JA ; Lamont, RF ; Wu, C ; Heidemann, LN ; Ibsen, MH ; Laursen, JB ; Ovesen, PG ; Rorbye, C ; Tanvig, M ; Joergensen, JS</creatorcontrib><description>Objective
To evaluate the reduction of surgical site infections by prophylactic incisional negative pressure wound therapy compared with standard postoperative dressings in obese women giving birth by caesarean section.
Design
Multicentre randomised controlled trial.
Setting
Five hospitals in Denmark.
Population
Obese women (prepregnancy body mass index (BMI) ≥30 kg/m2) undergoing elective or emergency caesarean section.
Method
The participants were randomly assigned to incisional negative pressure wound therapy or a standard dressing after caesarean section and analysed by intention‐to‐treat. Blinding was not possible due to the nature of the intervention.
Main outcome measures
The primary outcome was surgical site infection requiring antibiotic treatment within the first 30 days after surgery. Secondary outcomes included wound exudate, dehiscence and health‐related quality of life.
Results
Incisional negative pressure wound therapy was applied to 432 women and 444 women had a standard dressing. Demographics were similar between groups. Surgical site infection occurred in 20 (4.6%) women treated with incisional negative pressure wound therapy and in 41 (9.2%) women treated with a standard dressing (relative risk 0.50, 95% CI 0.30–0.84; number needed to treat 22; P = 0.007). The effect remained statistically significant when adjusted for BMI and other potential risk factors. Incisional negative pressure wound therapy significantly reduced wound exudate whereas no difference was found for dehiscence and quality of life between the two groups.
Conclusion
Prophylactic use of incisional negative pressure wound therapy reduced the risk of surgical site infection in obese women giving birth by caesarean section.
Tweetable
RCT: prophylactic incisional NPWT versus standard dressings postcaesarean in 876 women significantly reduces the risk of SSI.
Tweetable
RCT: prophylactic incisional NPWT versus standard dressings postcaesarean in 876 women significantly reduces the risk of SSI.</description><identifier>ISSN: 1470-0328</identifier><identifier>ISSN: 1471-0528</identifier><identifier>EISSN: 1471-0528</identifier><identifier>DOI: 10.1111/1471-0528.15413</identifier><identifier>PMID: 30066454</identifier><language>eng</language><publisher>England: Wiley Subscription Services, Inc</publisher><subject>Adult ; Antibiotics ; Bandages - statistics & numerical data ; Birth ; Body mass index ; Caesarean section ; Cesarean section ; Cesarean Section - adverse effects ; Clinical trials ; Dehiscence ; Demography ; Denmark ; Dressings ; Evidence-based medicine ; Female ; General Obstetrics ; Humans ; incisional negative pressure wound therapy ; Infections ; Negative-Pressure Wound Therapy - methods ; Obesity ; Obesity - complications ; Obesity - surgery ; Pregnancy ; Pregnancy Complications - surgery ; Pressure ; Quality of life ; Risk Factors ; Standard of Care - statistics & numerical data ; Statistical analysis ; Surgery ; surgical site infection ; Surgical site infections ; Surgical Wound Infection - etiology ; Surgical Wound Infection - prevention & control ; Treatment Outcome ; Womens health ; Wound Healing ; Wounds</subject><ispartof>BJOG : an international journal of obstetrics and gynaecology, 2019-04, Vol.126 (5), p.628-635</ispartof><rights>2018 The Authors. published by John Wiley & Sons Ltd on behalf of Royal College of Obstetricians and Gynaecologists</rights><rights>2018 The Authors. BJOG: An International Journal of Obstetrics and Gynaecology published by John Wiley & Sons Ltd on behalf of Royal College of Obstetricians and Gynaecologists.</rights><rights>Copyright © 2019 Royal College of Obstetricians and Gynaecologists</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4673-fa89cf8fa58ef427849019775eca5634bd65040195f2c4a211f2201194b597663</citedby><cites>FETCH-LOGICAL-c4673-fa89cf8fa58ef427849019775eca5634bd65040195f2c4a211f2201194b597663</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2F1471-0528.15413$$EPDF$$P50$$Gwiley$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2F1471-0528.15413$$EHTML$$P50$$Gwiley$$Hfree_for_read</linktohtml><link.rule.ids>230,314,777,781,882,1412,27905,27906,45555,45556</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30066454$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hyldig, N</creatorcontrib><creatorcontrib>Vinter, CA</creatorcontrib><creatorcontrib>Kruse, M</creatorcontrib><creatorcontrib>Mogensen, O</creatorcontrib><creatorcontrib>Bille, C</creatorcontrib><creatorcontrib>Sorensen, JA</creatorcontrib><creatorcontrib>Lamont, RF</creatorcontrib><creatorcontrib>Wu, C</creatorcontrib><creatorcontrib>Heidemann, LN</creatorcontrib><creatorcontrib>Ibsen, MH</creatorcontrib><creatorcontrib>Laursen, JB</creatorcontrib><creatorcontrib>Ovesen, PG</creatorcontrib><creatorcontrib>Rorbye, C</creatorcontrib><creatorcontrib>Tanvig, M</creatorcontrib><creatorcontrib>Joergensen, JS</creatorcontrib><title>Prophylactic incisional negative pressure wound therapy reduces the risk of surgical site infection after caesarean section in obese women: a pragmatic randomised clinical trial</title><title>BJOG : an international journal of obstetrics and gynaecology</title><addtitle>BJOG</addtitle><description>Objective
To evaluate the reduction of surgical site infections by prophylactic incisional negative pressure wound therapy compared with standard postoperative dressings in obese women giving birth by caesarean section.
Design
Multicentre randomised controlled trial.
Setting
Five hospitals in Denmark.
Population
Obese women (prepregnancy body mass index (BMI) ≥30 kg/m2) undergoing elective or emergency caesarean section.
Method
The participants were randomly assigned to incisional negative pressure wound therapy or a standard dressing after caesarean section and analysed by intention‐to‐treat. Blinding was not possible due to the nature of the intervention.
Main outcome measures
The primary outcome was surgical site infection requiring antibiotic treatment within the first 30 days after surgery. Secondary outcomes included wound exudate, dehiscence and health‐related quality of life.
Results
Incisional negative pressure wound therapy was applied to 432 women and 444 women had a standard dressing. Demographics were similar between groups. Surgical site infection occurred in 20 (4.6%) women treated with incisional negative pressure wound therapy and in 41 (9.2%) women treated with a standard dressing (relative risk 0.50, 95% CI 0.30–0.84; number needed to treat 22; P = 0.007). The effect remained statistically significant when adjusted for BMI and other potential risk factors. Incisional negative pressure wound therapy significantly reduced wound exudate whereas no difference was found for dehiscence and quality of life between the two groups.
Conclusion
Prophylactic use of incisional negative pressure wound therapy reduced the risk of surgical site infection in obese women giving birth by caesarean section.
Tweetable
RCT: prophylactic incisional NPWT versus standard dressings postcaesarean in 876 women significantly reduces the risk of SSI.
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RCT: prophylactic incisional NPWT versus standard dressings postcaesarean in 876 women significantly reduces the risk of SSI.</description><subject>Adult</subject><subject>Antibiotics</subject><subject>Bandages - statistics & numerical data</subject><subject>Birth</subject><subject>Body mass index</subject><subject>Caesarean section</subject><subject>Cesarean section</subject><subject>Cesarean Section - adverse effects</subject><subject>Clinical trials</subject><subject>Dehiscence</subject><subject>Demography</subject><subject>Denmark</subject><subject>Dressings</subject><subject>Evidence-based medicine</subject><subject>Female</subject><subject>General Obstetrics</subject><subject>Humans</subject><subject>incisional negative pressure wound therapy</subject><subject>Infections</subject><subject>Negative-Pressure Wound Therapy - methods</subject><subject>Obesity</subject><subject>Obesity - complications</subject><subject>Obesity - surgery</subject><subject>Pregnancy</subject><subject>Pregnancy Complications - surgery</subject><subject>Pressure</subject><subject>Quality of life</subject><subject>Risk Factors</subject><subject>Standard of Care - statistics & numerical data</subject><subject>Statistical analysis</subject><subject>Surgery</subject><subject>surgical site infection</subject><subject>Surgical site infections</subject><subject>Surgical Wound Infection - etiology</subject><subject>Surgical Wound Infection - prevention & control</subject><subject>Treatment Outcome</subject><subject>Womens health</subject><subject>Wound Healing</subject><subject>Wounds</subject><issn>1470-0328</issn><issn>1471-0528</issn><issn>1471-0528</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>24P</sourceid><sourceid>WIN</sourceid><sourceid>EIF</sourceid><recordid>eNqFks2P1CAYhxujcdfVszdD4sVLd6F8tPVgsm78zCbrQc_kHfoyw9pChXY382f5H0pnxol6kQvw8vAA-VEUzxk9Z7ldMFGzksqqOWdSMP6gOD1WHu7GtKS8ak6KJyndUspURfnj4oRTqpSQ4rT4-SWGcbPtwUzOEOeNSy546InHNUzuDskYMaU5IrkPs-_ItMEI45ZE7GaDaZmT6NJ3EizJ2NqZvDm5CbPMYrYGT8BOGIkBTBARPEmHuvMkrDAt6gH9awL5MFgPsFwlgu_C4BJ2xPTO77RTdNA_LR5Z6BM-O_Rnxbf3775efSyvbz58urq8Lo1QNS8tNK2xjQXZoBVV3YiWsrauJRqQiotVpyQVuSRtZQRUjNmqooy1YiXbWil-VrzZe8d5NWBn0E8Rej1GN0Dc6gBO_73i3Uavw51WslFM0Sx4dRDE8GPGNOn8HIN9Dx7DnHRFmxwal5xl9OU_6G2YY44hU6ypayZ522TqYk-ZGFKKaI-XYVQv30Ev4eslfL37DnnHiz_fcOR_558BuQfuXY_b__n02883e_EvzTzDHA</recordid><startdate>201904</startdate><enddate>201904</enddate><creator>Hyldig, N</creator><creator>Vinter, CA</creator><creator>Kruse, M</creator><creator>Mogensen, O</creator><creator>Bille, C</creator><creator>Sorensen, JA</creator><creator>Lamont, RF</creator><creator>Wu, C</creator><creator>Heidemann, LN</creator><creator>Ibsen, MH</creator><creator>Laursen, JB</creator><creator>Ovesen, PG</creator><creator>Rorbye, C</creator><creator>Tanvig, M</creator><creator>Joergensen, JS</creator><general>Wiley Subscription Services, Inc</general><general>John Wiley and Sons Inc</general><scope>24P</scope><scope>WIN</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QP</scope><scope>ASE</scope><scope>FPQ</scope><scope>K6X</scope><scope>K9.</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>201904</creationdate><title>Prophylactic incisional negative pressure wound therapy reduces the risk of surgical site infection after caesarean section in obese women: a pragmatic randomised clinical trial</title><author>Hyldig, N ; Vinter, CA ; Kruse, M ; Mogensen, O ; Bille, C ; Sorensen, JA ; Lamont, RF ; Wu, C ; Heidemann, LN ; Ibsen, MH ; Laursen, JB ; Ovesen, PG ; Rorbye, C ; Tanvig, M ; Joergensen, JS</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4673-fa89cf8fa58ef427849019775eca5634bd65040195f2c4a211f2201194b597663</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Adult</topic><topic>Antibiotics</topic><topic>Bandages - statistics & numerical data</topic><topic>Birth</topic><topic>Body mass index</topic><topic>Caesarean section</topic><topic>Cesarean section</topic><topic>Cesarean Section - adverse effects</topic><topic>Clinical trials</topic><topic>Dehiscence</topic><topic>Demography</topic><topic>Denmark</topic><topic>Dressings</topic><topic>Evidence-based medicine</topic><topic>Female</topic><topic>General Obstetrics</topic><topic>Humans</topic><topic>incisional negative pressure wound therapy</topic><topic>Infections</topic><topic>Negative-Pressure Wound Therapy - methods</topic><topic>Obesity</topic><topic>Obesity - complications</topic><topic>Obesity - surgery</topic><topic>Pregnancy</topic><topic>Pregnancy Complications - surgery</topic><topic>Pressure</topic><topic>Quality of life</topic><topic>Risk Factors</topic><topic>Standard of Care - statistics & numerical data</topic><topic>Statistical analysis</topic><topic>Surgery</topic><topic>surgical site infection</topic><topic>Surgical site infections</topic><topic>Surgical Wound Infection - etiology</topic><topic>Surgical Wound Infection - prevention & control</topic><topic>Treatment Outcome</topic><topic>Womens health</topic><topic>Wound Healing</topic><topic>Wounds</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hyldig, N</creatorcontrib><creatorcontrib>Vinter, CA</creatorcontrib><creatorcontrib>Kruse, M</creatorcontrib><creatorcontrib>Mogensen, O</creatorcontrib><creatorcontrib>Bille, C</creatorcontrib><creatorcontrib>Sorensen, JA</creatorcontrib><creatorcontrib>Lamont, RF</creatorcontrib><creatorcontrib>Wu, C</creatorcontrib><creatorcontrib>Heidemann, LN</creatorcontrib><creatorcontrib>Ibsen, MH</creatorcontrib><creatorcontrib>Laursen, JB</creatorcontrib><creatorcontrib>Ovesen, PG</creatorcontrib><creatorcontrib>Rorbye, C</creatorcontrib><creatorcontrib>Tanvig, M</creatorcontrib><creatorcontrib>Joergensen, JS</creatorcontrib><collection>Wiley Online Library Open Access</collection><collection>Wiley Free Content</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>British Nursing Index</collection><collection>British Nursing Index (BNI) (1985 to Present)</collection><collection>British Nursing Index</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>BJOG : an international journal of obstetrics and gynaecology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hyldig, N</au><au>Vinter, CA</au><au>Kruse, M</au><au>Mogensen, O</au><au>Bille, C</au><au>Sorensen, JA</au><au>Lamont, RF</au><au>Wu, C</au><au>Heidemann, LN</au><au>Ibsen, MH</au><au>Laursen, JB</au><au>Ovesen, PG</au><au>Rorbye, C</au><au>Tanvig, M</au><au>Joergensen, JS</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prophylactic incisional negative pressure wound therapy reduces the risk of surgical site infection after caesarean section in obese women: a pragmatic randomised clinical trial</atitle><jtitle>BJOG : an international journal of obstetrics and gynaecology</jtitle><addtitle>BJOG</addtitle><date>2019-04</date><risdate>2019</risdate><volume>126</volume><issue>5</issue><spage>628</spage><epage>635</epage><pages>628-635</pages><issn>1470-0328</issn><issn>1471-0528</issn><eissn>1471-0528</eissn><abstract>Objective
To evaluate the reduction of surgical site infections by prophylactic incisional negative pressure wound therapy compared with standard postoperative dressings in obese women giving birth by caesarean section.
Design
Multicentre randomised controlled trial.
Setting
Five hospitals in Denmark.
Population
Obese women (prepregnancy body mass index (BMI) ≥30 kg/m2) undergoing elective or emergency caesarean section.
Method
The participants were randomly assigned to incisional negative pressure wound therapy or a standard dressing after caesarean section and analysed by intention‐to‐treat. Blinding was not possible due to the nature of the intervention.
Main outcome measures
The primary outcome was surgical site infection requiring antibiotic treatment within the first 30 days after surgery. Secondary outcomes included wound exudate, dehiscence and health‐related quality of life.
Results
Incisional negative pressure wound therapy was applied to 432 women and 444 women had a standard dressing. Demographics were similar between groups. Surgical site infection occurred in 20 (4.6%) women treated with incisional negative pressure wound therapy and in 41 (9.2%) women treated with a standard dressing (relative risk 0.50, 95% CI 0.30–0.84; number needed to treat 22; P = 0.007). The effect remained statistically significant when adjusted for BMI and other potential risk factors. Incisional negative pressure wound therapy significantly reduced wound exudate whereas no difference was found for dehiscence and quality of life between the two groups.
Conclusion
Prophylactic use of incisional negative pressure wound therapy reduced the risk of surgical site infection in obese women giving birth by caesarean section.
Tweetable
RCT: prophylactic incisional NPWT versus standard dressings postcaesarean in 876 women significantly reduces the risk of SSI.
Tweetable
RCT: prophylactic incisional NPWT versus standard dressings postcaesarean in 876 women significantly reduces the risk of SSI.</abstract><cop>England</cop><pub>Wiley Subscription Services, Inc</pub><pmid>30066454</pmid><doi>10.1111/1471-0528.15413</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1470-0328 |
| ispartof | BJOG : an international journal of obstetrics and gynaecology, 2019-04, Vol.126 (5), p.628-635 |
| issn | 1470-0328 1471-0528 1471-0528 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6586160 |
| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Adult Antibiotics Bandages - statistics & numerical data Birth Body mass index Caesarean section Cesarean section Cesarean Section - adverse effects Clinical trials Dehiscence Demography Denmark Dressings Evidence-based medicine Female General Obstetrics Humans incisional negative pressure wound therapy Infections Negative-Pressure Wound Therapy - methods Obesity Obesity - complications Obesity - surgery Pregnancy Pregnancy Complications - surgery Pressure Quality of life Risk Factors Standard of Care - statistics & numerical data Statistical analysis Surgery surgical site infection Surgical site infections Surgical Wound Infection - etiology Surgical Wound Infection - prevention & control Treatment Outcome Womens health Wound Healing Wounds |
| title | Prophylactic incisional negative pressure wound therapy reduces the risk of surgical site infection after caesarean section in obese women: a pragmatic randomised clinical trial |
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