Inflammatory Biomarkers and Risk of Schizophrenia: A 2-Sample Mendelian Randomization Study

IMPORTANCE: Positive associations between inflammatory biomarkers and risk of psychiatric disorders, including schizophrenia, have been reported in observational studies. However, conventional observational studies are prone to bias, such as reverse causation and residual confounding, thus limiting...

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Veröffentlicht in:	JAMA psychiatry (Chicago, Ill.) Ill.), 2017-12, Vol.74 (12), p.1226-1233
Hauptverfasser:	Hartwig, Fernando Pires, Borges, Maria Carolina, Horta, Bernardo Lessa, Bowden, Jack, Davey Smith, George
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biomarkers Biomarkers - analysis C-Reactive Protein - genetics Clinical trials Epidemiology Female Genetic Association Studies Genetic Predisposition to Disease Genetic Variation Genome-Wide Association Study Humans Inflammation Inflammation - genetics Interleukin 1 Receptor Antagonist Protein - genetics Male Mendelian Randomization Analysis Middle Aged Online First Original Investigation Protective Factors Receptors, Interleukin-6 - genetics Schizophrenia Schizophrenia - epidemiology Schizophrenia - genetics Variables
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