The immunosuppressant FK506 increases the rate of axonal regeneration in rat sciatic nerve

The axonal regenerative properties of the new immunosuppressant drug FK506 (tacrolimus) are further explored in this continuing study. In an initial report (Gold et al., 1994a), we described the ability of FK506 to reduce the time until return of function in the hind feet of rats following a sciatic...

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Veröffentlicht in:	The Journal of neuroscience 1995-11, Vol.15 (11), p.7509-7516
Hauptverfasser:	Gold, BG, Katoh, K, Storm-Dickerson, T
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Axons - drug effects Axons - physiology Immunosuppressive Agents - pharmacology Male Nerve Regeneration - drug effects Neurons, Afferent - drug effects Neurons, Afferent - physiology Rats Rats, Sprague-Dawley Sciatic Nerve - cytology Sciatic Nerve - drug effects Tacrolimus - pharmacology Time Factors
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