Axotomy-induced axonal degeneration is mediated by calcium influx through ion-specific channels

We examined the role of extracellular calcium entry, the possible involvement of axonal calcium channels, and the potential protective effect of calcium channel and calpain antagonists in axotomy-induced axonal degeneration using murine dorsal root ganglia in cell culture. We found that calcium entr...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of neuroscience 1995-10, Vol.15 (10), p.6445-6452
Hauptverfasser:	George, EB, Glass, JD, Griffin, JW
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Axons - drug effects Axons - physiology Bepridil - pharmacology Calcium - metabolism Calcium Channel Blockers - pharmacology Calcium Channels - physiology Calpain - physiology Culture Techniques Ganglia, Spinal - drug effects Ganglia, Spinal - physiology Ganglia, Spinal - ultrastructure Mice Nerve Degeneration - drug effects omega-Conotoxin GVIA Peptides - pharmacology Tetrodotoxin - pharmacology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!