GABAergic and developmental influences on homosynaptic LTD and depotentiation in rat hippocampus

Low-frequency (1 Hz) stimulation (LFS) was used to elicit long-term depression (LTD) or depotentiation of excitatory transmission of the Schaffer collateral pathway in the CA1 region of the rat hippocampus. Both LTD and depotentiation were found to be homosynaptic and NMDA receptor (NMDAR) dependent...

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Veröffentlicht in:	The Journal of neuroscience 1995-02, Vol.15 (2), p.1577-1586
Hauptverfasser:	Wagner, JJ, Alger, BE
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging - physiology Animals Electric Stimulation - methods Electrophysiology GABA-A Receptor Antagonists GABA-B Receptor Antagonists gamma-Aminobutyric Acid - physiology Hippocampus - drug effects Hippocampus - growth & development Hippocampus - physiology Long-Term Potentiation Organophosphorus Compounds - pharmacology Rats Rats, Sprague-Dawley Receptors, GABA-A - physiology Receptors, GABA-B - physiology Synapses - physiology
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