Neurotrophin-4/5 (NT-4/5) and brain-derived neurotrophic factor (BDNF) act at later stages of cerebellar granule cell differentiation

The developing cerebellum expresses genes which encode for both neurotrophins and their receptors. The present study was designed to determine at what stages during cerebellar granule cell neurogenesis neurotrophin family molecules may act. We report here that in purified, well-characterized granule...

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Veröffentlicht in:	The Journal of neuroscience 1995-04, Vol.15 (4), p.2656-2667
Hauptverfasser:	Gao, WQ, Zheng, JL, Karihaloo, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Brain-Derived Neurotrophic Factor Bromodeoxyuridine Carbazoles - pharmacology Cell Aggregation Cell Communication Cell Differentiation - drug effects Cell Division - drug effects Cell Survival - drug effects Cells, Cultured Cerebellum - cytology Cerebellum - physiology DNA - biosynthesis Indole Alkaloids Insulin-Like Growth Factor I - pharmacology Mammalia Mice Mice, Inbred C57BL Mice, Neurologic Mutants Nerve Growth Factors - pharmacology Nerve Tissue Proteins - pharmacology Neurites - drug effects Neurites - physiology Neurons - cytology Neurons - drug effects Neurons - physiology Neurotrophin 3 Protein Kinase C - antagonists & inhibitors Protein-Tyrosine Kinases - antagonists & inhibitors
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