Ultrastructural immunolabeling shows prominent presynaptic vesicular localization of delta-opioid receptor within both enkephalin- and nonenkephalin-containing axon terminals in the superficial layers of the rat cervical spinal cord

Opioid peptides, Met5- and Leu5-enkephalin, are known endogenous ligands for the delta-opioid receptor (DOR) associated with opioid analgesia at the spinal level. To determine the cellular sites for DOR-mediated actions, we examined the ultrastructural localization of DOR and Met5-enkephalin (ME) in...

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Veröffentlicht in:The Journal of neuroscience 1995-09, Vol.15 (9), p.5976-5988
Hauptverfasser: Cheng, PY, Svingos, AL, Wang, H, Clarke, CL, Jenab, S, Beczkowska, IW, Inturrisi, CE, Pickel, VM
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Sprache:eng
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