Astrocyte Na+ channels are required for maintenance of Na+/K(+)-ATPase activity

Astrocytes in vitro and in situ have been shown to express voltage-activated ion channels previously thought to be restricted to excitable cells, including voltage-activated Na+, Ca2+, and K+ channels. However, unlike neurons, astrocytes do not generate action potentials, and the functional role of...

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Veröffentlicht in:	The Journal of neuroscience 1994-05, Vol.14 (5), p.2464-2475
Hauptverfasser:	Sontheimer, H, Fernandez-Marques, E, Ullrich, N, Pappas, CA, Waxman, SG
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Newborn Astrocytes - drug effects Astrocytes - enzymology Astrocytes - physiology Astrocytoma Cell Line Cells, Cultured Electrophysiology - methods Ganglia, Spinal - cytology Ganglia, Spinal - physiology Glioma Membrane Potentials - drug effects Membrane Potentials - physiology Models, Biological Ouabain - pharmacology Rats Rats, Sprague-Dawley Rubidium - metabolism Sodium - metabolism Sodium Channels - drug effects Sodium Channels - physiology Sodium-Potassium-Exchanging ATPase - metabolism Strophanthidin - pharmacology Tetrodotoxin - pharmacology Time Factors Tumor Cells, Cultured
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