Suppression of sodium channel function in differentiating C2 muscle cells stably overexpressing rat androgen receptors

Differentiation of skeletal muscle and the formation of the neuromuscular junction are regulated by steroid hormones. The effects of androgens on ion channel proteins central to neuromuscular signalling have been investigated in differentiating mouse muscle C2 cells and in C2 cells that stably overe...

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Veröffentlicht in:	The Journal of neuroscience 1994-02, Vol.14 (2), p.763-773
Hauptverfasser:	Tabb, JS, Fanger, GR, Wilson, EM, Maue, RA, Henderson, LP
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholine - pharmacology Androgen Antagonists - pharmacology Animals Biological and medical sciences Bungarotoxins - metabolism Cell Differentiation Cell Line Dihydrotestosterone - pharmacology Flutamide - analogs & derivatives Flutamide - pharmacology Fundamental and applied biological sciences. Psychology Gene Expression Metribolone - metabolism Mice Muscles - cytology Muscles - metabolism Muscles - physiology Rats Receptors, Androgen - biosynthesis Receptors, Androgen - drug effects Receptors, Androgen - physiology Receptors, Cholinergic - biosynthesis Receptors, Cholinergic - drug effects Receptors, Cholinergic - metabolism Sodium Channels - drug effects Sodium Channels - physiology Striated muscle. Tendons Transfection Vertebrates: osteoarticular system, musculoskeletal system
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