Impaired Parallel Fiber→Purkinje Cell Synapse Stabilization during Cerebellar Development of Mutant Mice Lacking the Glutamate Receptor δ2 Subunit

The glutamate receptor δ2 subunit (GluRδ2) is specifically expressed in cerebellar Purkinje cells (PCs) from early developmental stages and is selectively localized at dendritic spines forming synapses with parallel fibers (PFs). Targeted disruption of the GluRδ2 gene leads to a significant reductio...

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Veröffentlicht in:The Journal of neuroscience 1997-12, Vol.17 (24), p.9613-9623
Hauptverfasser: Kurihara, Hideo, Hashimoto, Kouichi, Kano, Masanobu, Takayama, Chitoshi, Sakimura, Kenji, Mishina, Masayoshi, Inoue, Yoshiro, Watanabe, Masahiko
Format: Artikel
Sprache:eng
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