Cyclic AMP-dependent phosphorylation of a neuronal acetylcholine receptor alpha-type subunit

Chick ciliary ganglion neurons have nicotinic acetylcholine receptors (AChRs) that mediate synaptic transmission through the ganglion. A cAMP-dependent process has previously been shown to enhance the ACh response of the neurons 2- to 3-fold without requiring the synthesis of new receptors. We show...

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Veröffentlicht in:	The Journal of neuroscience 1990-10, Vol.10 (10), p.3255-3262
Hauptverfasser:	Vijayaraghavan, S, Schmid, HA, Halvorsen, SW, Berg, DK
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Methyl-3-isobutylxanthine - pharmacology 8-Bromo Cyclic Adenosine Monophosphate - pharmacology Animals Biological and medical sciences Chick Embryo Cyclic AMP - pharmacology Electrophoresis, Polyacrylamide Gel Fundamental and applied biological sciences. Psychology Ganglia, Parasympathetic - metabolism Immunosorbent Techniques Kinetics Neurons - metabolism Peripheral nervous system. Autonomic nervous system. Neuromuscular transmission. Ganglionic transmission. Electric organ Phosphates - metabolism Phosphorylation Receptors, Cholinergic - metabolism Vertebrates: nervous system and sense organs
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