A GABAergic inhibitory component within the hippocampal commissural pathway
Previous results from immunocytochemical and retrograde transport studies indicated that some GABAergic neurons in the hilus of the dentate gyrus may have axonal projections through the hippocampal commissure. This study has utilized a combined immunocytochemical and retrograde transport method as w...
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| Veröffentlicht in: | The Journal of neuroscience 1986-12, Vol.6 (12), p.3492-3498 |
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| container_issue | 12 |
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| container_title | The Journal of neuroscience |
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| creator | Ribak, CE Seress, L Peterson, GM Seroogy, KB Fallon, JH Schmued, LC |
| description | Previous results from immunocytochemical and retrograde transport studies indicated that some GABAergic neurons in the hilus of the dentate gyrus may have axonal projections through the hippocampal commissure. This study has utilized a combined immunocytochemical and retrograde transport method as well as 2 anterograde electron-microscopic methods to determine the existence of this projection in rats. Combined tracer and immunofluorescence studies showed several double-labeled GABAergic neurons in the hilus contralateral to the injection site. The electron-microscopic studies revealed both degenerating and HRP-labeled commissural axons that formed symmetric synapses, the type shown to be formed by GABAergic terminals in the hippocampus. These data demonstrate a GABAergic component within the hippocampal commissural pathway and add further evidence that cortical GABAergic terminals are not derived exclusively from intrinsic neurons. |
| doi_str_mv | 10.1523/jneurosci.06-12-03492.1986 |
| format | Article |
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Psychology ; gamma-Aminobutyric Acid - physiology ; Hippocampus - cytology ; Histocytochemistry ; Horseradish Peroxidase ; Male ; Microscopy, Electron ; Neurons - cytology ; Rats ; Rats, Inbred Strains ; Synapses ; Vertebrates: nervous system and sense organs</subject><ispartof>The Journal of neuroscience, 1986-12, Vol.6 (12), p.3492-3498</ispartof><rights>1987 INIST-CNRS</rights><rights>1986 by Society for Neuroscience 1986</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c635t-7e0d6ac34163a45302493a484e61e5b9b8066e2cd629cef5333bb46bb87e4b553</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6568657/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6568657/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=7997820$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2432200$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ribak, CE</creatorcontrib><creatorcontrib>Seress, L</creatorcontrib><creatorcontrib>Peterson, GM</creatorcontrib><creatorcontrib>Seroogy, KB</creatorcontrib><creatorcontrib>Fallon, JH</creatorcontrib><creatorcontrib>Schmued, LC</creatorcontrib><title>A GABAergic inhibitory component within the hippocampal commissural pathway</title><title>The Journal of neuroscience</title><addtitle>J Neurosci</addtitle><description>Previous results from immunocytochemical and retrograde transport studies indicated that some GABAergic neurons in the hilus of the dentate gyrus may have axonal projections through the hippocampal commissure. 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Pathways and receptors</subject><subject>Female</subject><subject>Fluorescent Antibody Technique</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>gamma-Aminobutyric Acid - physiology</subject><subject>Hippocampus - cytology</subject><subject>Histocytochemistry</subject><subject>Horseradish Peroxidase</subject><subject>Male</subject><subject>Microscopy, Electron</subject><subject>Neurons - cytology</subject><subject>Rats</subject><subject>Rats, Inbred Strains</subject><subject>Synapses</subject><subject>Vertebrates: nervous system and sense organs</subject><issn>0270-6474</issn><issn>1529-2401</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1986</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkU9v1DAQxS0EKkvhIyBFCHHLMv4fc0BaVqUUKioBPVuO17txlcTBToj22-NtVwucOM1I85s3b_QQeoVhiTmhb-96N8WQrF-CKDEpgTJFllhV4hFaZEKVhAF-jBZAJJSCSfYUPUvpDgAkYHmGzgijhAAs0JdVcbn6sHJx523h-8bXfgxxX9jQDaF3_VjMfmx8X4yNKxo_DMGabjDtAeh8SlPM_WDGZjb75-jJ1rTJvTjWc3T78eLH-lN5fXN5tV5dl1ZQPpbSwUYYSxkW1DBOgTCVm4o5gR2vVV2BEI7YjSDKui2nlNY1E3VdScdqzuk5ev-gO0x15zY2u8wu9BB9Z-JeB-P1v5PeN3oXfmnBRSW4zAJvjgIx_JxcGnV-xbq2Nb0LU9JSEkyUEP8FMROSY8Uy-O4BtDmXFN325AaDPmSmP3-9uP128319pUFoTPR9ZvqQWV5--fc_p9VjSHn--jg3yZp2G01vfTphUilZEfhjtvG7ZvbR6dSZts2iWM_zfH_1cJT-BorIsBA</recordid><startdate>19861201</startdate><enddate>19861201</enddate><creator>Ribak, CE</creator><creator>Seress, L</creator><creator>Peterson, GM</creator><creator>Seroogy, KB</creator><creator>Fallon, JH</creator><creator>Schmued, LC</creator><general>Soc Neuroscience</general><general>Society for Neuroscience</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>19861201</creationdate><title>A GABAergic inhibitory component within the hippocampal commissural pathway</title><author>Ribak, CE ; Seress, L ; Peterson, GM ; Seroogy, KB ; Fallon, JH ; Schmued, LC</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c635t-7e0d6ac34163a45302493a484e61e5b9b8066e2cd629cef5333bb46bb87e4b553</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1986</creationdate><topic>Animals</topic><topic>Axonal Transport</topic><topic>Biological and medical sciences</topic><topic>Central nervous system</topic><topic>Central neurotransmission. 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Psychology</topic><topic>gamma-Aminobutyric Acid - physiology</topic><topic>Hippocampus - cytology</topic><topic>Histocytochemistry</topic><topic>Horseradish Peroxidase</topic><topic>Male</topic><topic>Microscopy, Electron</topic><topic>Neurons - cytology</topic><topic>Rats</topic><topic>Rats, Inbred Strains</topic><topic>Synapses</topic><topic>Vertebrates: nervous system and sense organs</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ribak, CE</creatorcontrib><creatorcontrib>Seress, L</creatorcontrib><creatorcontrib>Peterson, GM</creatorcontrib><creatorcontrib>Seroogy, KB</creatorcontrib><creatorcontrib>Fallon, JH</creatorcontrib><creatorcontrib>Schmued, LC</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>The Journal of neuroscience</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ribak, CE</au><au>Seress, L</au><au>Peterson, GM</au><au>Seroogy, KB</au><au>Fallon, JH</au><au>Schmued, LC</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A GABAergic inhibitory component within the hippocampal commissural pathway</atitle><jtitle>The Journal of neuroscience</jtitle><addtitle>J Neurosci</addtitle><date>1986-12-01</date><risdate>1986</risdate><volume>6</volume><issue>12</issue><spage>3492</spage><epage>3498</epage><pages>3492-3498</pages><issn>0270-6474</issn><eissn>1529-2401</eissn><coden>JNRSDS</coden><abstract>Previous results from immunocytochemical and retrograde transport studies indicated that some GABAergic neurons in the hilus of the dentate gyrus may have axonal projections through the hippocampal commissure. 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| ispartof | The Journal of neuroscience, 1986-12, Vol.6 (12), p.3492-3498 |
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| language | eng |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals; PubMed Central |
| subjects | Animals Axonal Transport Biological and medical sciences Central nervous system Central neurotransmission. Neuromudulation. Pathways and receptors Female Fluorescent Antibody Technique Fundamental and applied biological sciences. Psychology gamma-Aminobutyric Acid - physiology Hippocampus - cytology Histocytochemistry Horseradish Peroxidase Male Microscopy, Electron Neurons - cytology Rats Rats, Inbred Strains Synapses Vertebrates: nervous system and sense organs |
| title | A GABAergic inhibitory component within the hippocampal commissural pathway |
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